Chlorine in PDB 1tgx: X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes

The structure of X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes, PDB code: 1tgx was solved by A.Bilwes, B.Rees, D.Moras, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	5.00 / 1.55
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	78.670, 40.710, 56.020, 90.00, 117.08, 90.00
R / Rfree (%)	n/a / n/a

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 14;

Binding sites:

The binding sites of Chlorine atom in the X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes (pdb code 1tgx). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 14 binding sites of Chlorine where determined in the X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes, PDB code: 1tgx:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Chlorine binding site 1 out of 14 in the X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl102 b:39.8 occ:0.87 NZ A:LYS18 3.0 34.7 1.0 NZ A:LYS12 3.2 42.1 1.0 CD A:LYS18 3.8 22.7 1.0 CE A:LYS12 3.8 83.3 1.0 CD A:PRO15 3.9 19.1 1.0 CE A:LYS18 3.9 26.9 1.0 CG A:PRO15 4.1 19.3 1.0 CB A:CYS38 4.2 12.1 1.0 CD A:LYS12 4.5 33.4 1.0 O A:CYS38 4.6 19.4 1.0 O A:HOH268 4.7 42.3 1.0 SG A:CYS38 4.7 13.8 1.0

Chlorine binding site 2 out of 14 in the X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl120 b:17.4 occ:0.44 N A:LEU1 3.0 11.5 1.0 CA A:LEU1 3.8 4.9 1.0 C A:LEU1 3.9 9.6 1.0 CG A:LYS2 4.1 16.2 1.0 O A:LEU1 4.2 11.5 1.0 N A:LYS2 4.2 11.6 1.0 CE A:LYS2 4.5 34.1 1.0 OD1 A:ASP57 4.6 10.9 1.0 CG2 A:THR13 4.7 13.7 1.0 CD A:LYS2 4.7 20.2 1.0 O A:HOH261 4.8 16.6 1.0 OD2 A:ASP57 5.0 14.2 1.0 CB A:LYS2 5.0 10.8 1.0

Chlorine binding site 3 out of 14 in the X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl242 b:53.2 occ:0.78 NH2 A:ARG36 3.1 31.9 1.0 NZ C:LYS50 3.5 51.5 1.0 O A:HOH275 3.5 39.9 1.0 O C:HOH119 3.7 39.7 1.0 CD C:LYS50 3.9 41.4 1.0 NH1 A:ARG36 4.0 23.3 1.0 CZ A:ARG36 4.1 26.5 1.0 CB C:PRO30 4.1 34.4 1.0 CE C:LYS50 4.3 36.8 1.0 O A:HOH265 4.4 45.1 1.0

Chlorine binding site 4 out of 14 in the X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl245 b:70.0 occ:0.85 O A:HOH292 2.9 20.0 1.0 NH2 A:ARG27 3.3 47.5 1.0 NE A:ARG27 3.5 63.8 1.0 CZ A:ARG27 3.7 32.5 1.0 CD2 A:LEU47 3.8 23.8 1.0 CL A:CL260 4.1 74.6 0.9 CD A:ARG27 4.5 62.5 1.0 O B:LEU6 4.7 17.8 1.0 CG A:ARG27 4.8 32.4 1.0 NH1 A:ARG27 4.9 42.9 1.0

Chlorine binding site 5 out of 14 in the X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl260 b:74.6 occ:0.91 NH2 A:ARG27 2.8 47.5 1.0 CZ A:ARG27 3.9 32.5 1.0 CL A:CL245 4.1 70.0 0.8 NH1 A:ARG27 4.3 42.9 1.0 CD2 A:LEU47 4.4 23.8 1.0 NE A:ARG27 4.9 63.8 1.0

Chlorine binding site 6 out of 14 in the X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl102 b:62.5 occ:0.93 CL B:CL106 3.3 33.9 1.0 NZ B:LYS12 3.4 41.2 1.0 CE B:LYS12 3.6 53.5 1.0 CB B:CYS38 3.8 13.2 1.0 CD B:PRO15 3.8 17.6 1.0 CD B:LYS18 3.9 26.0 1.0 CL B:CL270 4.0 47.1 0.9 O B:CYS38 4.2 13.1 1.0 CG B:PRO15 4.3 26.9 1.0 SG B:CYS38 4.4 12.6 1.0 CD B:LYS12 4.5 43.8 1.0 CE B:LYS18 4.6 49.9 1.0 CA B:CYS38 4.7 11.4 1.0 N B:CYS38 4.8 15.0 1.0 C B:CYS38 4.8 13.4 1.0

Chlorine binding site 7 out of 14 in the X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl106 b:33.9 occ:0.96 NZ B:LYS12 3.1 41.2 1.0 N B:CYS38 3.2 15.0 1.0 CL B:CL102 3.3 62.5 0.9 O B:HOH289 3.6 41.9 1.0 CA B:GLY37 3.7 9.6 1.0 O B:CYS38 3.8 13.1 1.0 CE B:LYS12 3.9 53.5 1.0 CD B:LYS12 3.9 43.8 1.0 C B:GLY37 3.9 12.8 1.0 CA B:CYS38 4.2 11.4 1.0 CB B:CYS38 4.3 13.2 1.0 C B:CYS38 4.5 13.4 1.0 SG B:CYS38 4.8 12.6 1.0 N B:GLY37 5.0 12.9 1.0 NZ B:LYS35 5.0 36.9 1.0

Chlorine binding site 8 out of 14 in the X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 8 of X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl120 b:17.7 occ:1.00 NZ B:LYS2 2.9 22.9 1.0 N B:LEU1 3.2 11.5 1.0 C B:LEU1 3.9 15.7 1.0 CE B:LYS2 3.9 30.8 1.0 CA B:LEU1 4.0 10.8 1.0 CG B:LYS2 4.0 22.0 1.0 CD B:LYS2 4.0 31.4 1.0 O B:LEU1 4.1 12.9 1.0 CG2 B:THR13 4.3 14.2 1.0 N B:LYS2 4.4 13.2 1.0 O B:HOH273 4.8 18.8 1.0 CB B:LYS2 4.9 14.4 1.0 OD1 B:ASP57 4.9 9.3 1.0

Chlorine binding site 9 out of 14 in the X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 9 of X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl123 b:33.6 occ:0.96 O A:HOH291 3.1 38.6 1.0 NH1 B:ARG36 3.2 22.9 1.0 CD B:PRO33 3.8 27.7 1.0 NH2 B:ARG36 3.9 21.1 1.0 CG A:LYS50 4.0 19.7 1.0 CZ B:ARG36 4.0 23.6 1.0 CE A:LYS50 4.0 17.6 1.0 O A:HOH264 4.3 41.6 1.0 CG A:ARG27 4.3 32.4 1.0 CA A:ARG27 4.3 14.0 1.0 CG B:PRO33 4.3 36.0 1.0 CD A:LYS50 4.5 20.0 1.0 CB A:ARG27 4.5 18.0 1.0 N A:ALA28 4.6 19.7 1.0 CD2 B:LEU6 4.7 13.6 1.0

Chlorine binding site 10 out of 14 in the X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 10 of X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl206 b:84.2 occ:0.84 NZ B:LYS16 3.0 60.4 1.0 CE B:LYS16 3.3 40.8 1.0 O B:HOH315 3.9 33.7 1.0 CD B:LYS16 4.1 71.3 1.0

A.Bilwes, B.Rees, D.Moras, R.Menez, A.Menez. X-Ray Structure at 1.55 A of Toxin Gamma, A Cardiotoxin From Naja Nigricollis Venom. Crystal Packing Reveals A Model For Insertion Into Membranes. J.Mol.Biol. V. 239 122 1994.
ISSN: ISSN 0022-2836
PubMed: 8196041
DOI: 10.1006/JMBI.1994.1357