Chlorine in PDB 2a72: Structure of the Regulator of G-Protein Signaling Domain of RGS7

The structure of Structure of the Regulator of G-Protein Signaling Domain of RGS7, PDB code: 2a72 was solved by G.A.Schoch, C.Johansson, C.Phillips, J.Debreczeni, C.Smee, J.M.Elkins, M.Sundstrom, A.Edwards, C.Arrowsmith, F.Von Delft, O.Gileadi, D.A.Doyle, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	53.00 / 2.00
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	28.915, 106.033, 52.490, 90.00, 103.71, 90.00
R / Rfree (%)	18.4 / 24.9

The binding sites of Chlorine atom in the Structure of the Regulator of G-Protein Signaling Domain of RGS7 (pdb code 2a72). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of the Regulator of G-Protein Signaling Domain of RGS7, PDB code: 2a72:

Chlorine binding site 1 out of 1 in the Structure of the Regulator of G-Protein Signaling Domain of RGS7


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the Regulator of G-Protein Signaling Domain of RGS7 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl301 b:51.3 occ:1.00 NH2 A:ARG440 3.4 30.4 1.0 CD A:ARG437 3.6 39.2 1.0 O A:HOH101 3.9 29.0 1.0 NH1 A:ARG437 4.0 41.7 1.0 NE A:ARG440 4.1 26.2 1.0 CZ A:ARG440 4.2 28.8 1.0 CG A:ARG437 4.3 34.4 1.0 OE1 B:GLU354 4.6 39.3 1.0 NE A:ARG437 4.6 40.0 1.0 O A:HOH142 4.7 39.7 1.0 CZ A:ARG437 4.7 40.2 1.0

M.Soundararajan, F.S.Willard, A.J.Kimple, A.P.Turnbull, L.J.Ball, G.A.Schoch, C.Gileadi, O.Y.Fedorov, E.F.Dowler, V.A.Higman, S.Q.Hutsell, M.Sundstrom, D.A.Doyle, D.P.Siderovski. Structural Diversity in the Rgs Domain and Its Interaction with Heterotrimeric G Protein Alpha-Subunits. Proc.Natl.Acad.Sci.Usa V. 105 6457 2008.
ISSN: ISSN 0027-8424
PubMed: 18434541
DOI: 10.1073/PNAS.0801508105