Chlorine in PDB 2djg: Re-Determination of the Native Structure of Human Dipeptidyl Peptidase I (Cathepsin C)

All present enzymatic activity of Re-Determination of the Native Structure of Human Dipeptidyl Peptidase I (Cathepsin C):
3.4.14.1;

The structure of Re-Determination of the Native Structure of Human Dipeptidyl Peptidase I (Cathepsin C), PDB code: 2djg was solved by A.Molgaard, J.Arnau, C.Lauritzen, S.Larsen, G.Petersen, J.Pedersen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.04 / 2.05
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	87.479, 88.680, 114.350, 90.00, 90.00, 90.00
R / Rfree (%)	17.4 / 22.1

The binding sites of Chlorine atom in the Re-Determination of the Native Structure of Human Dipeptidyl Peptidase I (Cathepsin C) (pdb code 2djg). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Re-Determination of the Native Structure of Human Dipeptidyl Peptidase I (Cathepsin C), PDB code: 2djg:

Chlorine binding site 1 out of 1 in the Re-Determination of the Native Structure of Human Dipeptidyl Peptidase I (Cathepsin C)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Re-Determination of the Native Structure of Human Dipeptidyl Peptidase I (Cathepsin C) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl500 b:19.2 occ:1.00 OH B:TYR323 3.2 20.7 1.0 O C:HOH87 3.3 26.8 1.0 N B:TYR280 3.3 16.9 1.0 O C:HOH185 3.4 32.4 1.0 CD B:PRO279 3.6 19.4 1.0 CB B:PHE278 3.6 18.3 1.0 CE1 B:TYR323 3.6 17.9 1.0 CB B:TYR280 3.6 16.2 1.0 N B:PRO279 3.7 17.9 1.0 CG2 C:VAL431 3.7 20.9 1.0 CZ B:TYR323 3.9 17.7 1.0 CD2 B:PHE278 3.9 21.4 1.0 C B:PHE278 4.0 18.6 1.0 CD1 C:ILE429 4.0 17.4 1.0 CA B:TYR280 4.0 16.6 1.0 CA B:PHE278 4.1 18.0 1.0 C B:PRO279 4.2 18.1 1.0 CG1 C:ILE429 4.2 17.5 1.0 CG B:PHE278 4.2 19.8 1.0 CA B:PRO279 4.3 18.9 1.0 CB B:PRO279 4.3 19.1 1.0 CG B:PRO279 4.5 17.3 1.0 O B:PHE278 4.8 19.0 1.0 CD1 B:TYR323 4.8 16.7 1.0 CG2 A:ILE63 4.9 16.7 1.0 O C:ILE429 4.9 17.0 1.0 CB C:VAL431 5.0 19.6 1.0 CG B:TYR280 5.0 14.3 1.0

A.Molgaard, J.Arnau, C.Lauritzen, S.Larsen, G.Petersen, J.Pedersen. The Crystal Structure of Human Dipeptidyl Peptidase I (Cathepsin C) in Complex with the Inhibitor Gly-Phe-CHN2 Biochem.J. V. 401 645 2007.
ISSN: ISSN 0264-6021
PubMed: 17020538
DOI: 10.1042/BJ20061389