Chlorine in PDB 3m98: Crystal Structure of Human Carbonic Anhydrase Isozyme II with 5-(1H- Benzimidazol-1-Ylacetyl)-2-Chlorobenzenesulfonamide

Enzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 5-(1H- Benzimidazol-1-Ylacetyl)-2-Chlorobenzenesulfonamide

All present enzymatic activity of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 5-(1H- Benzimidazol-1-Ylacetyl)-2-Chlorobenzenesulfonamide:
4.2.1.1;

Protein crystallography data

The structure of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 5-(1H- Benzimidazol-1-Ylacetyl)-2-Chlorobenzenesulfonamide, PDB code: 3m98 was solved by S.Grazulis, E.Manakova, D.Golovenko, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	39.81 / 1.50
*Space group*	P 1 2₁ 1
*Cell size a, b, c (Å), α, β, γ (°)*	42.233, 41.112, 72.109, 90.00, 104.05, 90.00
*R / R_free (%)*	13.5 / 18.4

Other elements in 3m98:

The structure of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 5-(1H- Benzimidazol-1-Ylacetyl)-2-Chlorobenzenesulfonamide also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 5-(1H- Benzimidazol-1-Ylacetyl)-2-Chlorobenzenesulfonamide (pdb code 3m98). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 5-(1H- Benzimidazol-1-Ylacetyl)-2-Chlorobenzenesulfonamide, PDB code: 3m98:

Chlorine binding site 1 out of 1 in 3m98

Go back to

Chlorine Binding Sites List in 3m98

Chlorine binding site 1 out of 1 in the Crystal Structure of Human Carbonic Anhydrase Isozyme II with 5-(1H- Benzimidazol-1-Ylacetyl)-2-Chlorobenzenesulfonamide

Mono view

Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Carbonic Anhydrase Isozyme II with 5-(1H- Benzimidazol-1-Ylacetyl)-2-Chlorobenzenesulfonamide within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:Cl263 b:13.9 occ:1.00	CL21	A:E02263	0.0	13.9	1.0
	C16	A:E02263	1.7	13.4	1.0
	C17	A:E02263	2.7	15.2	1.0
	C15	A:E02263	2.7	9.6	1.0
	S19	A:E02263	3.2	11.2	1.0
	O22	A:E02263	3.2	9.8	1.0
	O20	A:E02263	3.2	10.4	1.0
	CG2	A:VAL143	3.4	8.7	1.0
	CD2	A:LEU198	3.6	16.2	1.0
	CD1	A:LEU141	3.7	9.1	1.0
	CG1	A:VAL121	3.9	9.2	1.0
	CG2	A:VAL121	3.9	8.8	1.0
	C14	A:E02263	4.0	12.4	1.0
	C18	A:E02263	4.0	18.6	1.0
	CG2	A:VAL207	4.4	8.7	1.0
	CB	A:VAL121	4.5	7.7	1.0
	C13	A:E02263	4.5	17.7	1.0
	CG	A:LEU198	4.6	15.8	1.0
	CA	A:LEU198	4.7	7.2	1.0
	CB	A:VAL143	4.7	8.6	1.0
	N23	A:E02263	4.8	9.8	1.0
	CB	A:LEU198	4.8	9.7	1.0
	CG	A:LEU141	5.0	9.2	1.0
	CG1	A:VAL143	5.0	9.4	1.0

Reference:

E.Capkauskaite, L.Baranauskiene, S.Grazulis, E.Manakova, D.Golovenko, D.Matulis. Crystal Structure of Human Carbonic Anhydrase Isozyme II with 5-(1H-Benzimidazol-1-Ylacetyl) -2-Chlorobenzenesulfonamide To Be Published.

Page generated: Sat Dec 12 09:54:40 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy