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Atomistry » Chlorine » PDB 3nb5-3nnu » 3nb5 » |
Chlorine in PDB 3nb5: Human Carbonic Anhydrase II in Complex with 2-(3-Chloro-4- Hydroxyphenyl)-N-(4-Sulfamoylphenethyl)AcetamideEnzymatic activity of Human Carbonic Anhydrase II in Complex with 2-(3-Chloro-4- Hydroxyphenyl)-N-(4-Sulfamoylphenethyl)Acetamide
All present enzymatic activity of Human Carbonic Anhydrase II in Complex with 2-(3-Chloro-4- Hydroxyphenyl)-N-(4-Sulfamoylphenethyl)Acetamide:
4.2.1.1; Protein crystallography data
The structure of Human Carbonic Anhydrase II in Complex with 2-(3-Chloro-4- Hydroxyphenyl)-N-(4-Sulfamoylphenethyl)Acetamide, PDB code: 3nb5
was solved by
A.Hofmann,
A.Osman,
R.A.Davis,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3nb5:
The structure of Human Carbonic Anhydrase II in Complex with 2-(3-Chloro-4- Hydroxyphenyl)-N-(4-Sulfamoylphenethyl)Acetamide also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Human Carbonic Anhydrase II in Complex with 2-(3-Chloro-4- Hydroxyphenyl)-N-(4-Sulfamoylphenethyl)Acetamide
(pdb code 3nb5). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Carbonic Anhydrase II in Complex with 2-(3-Chloro-4- Hydroxyphenyl)-N-(4-Sulfamoylphenethyl)Acetamide, PDB code: 3nb5: Chlorine binding site 1 out of 1 in 3nb5Go back to Chlorine Binding Sites List in 3nb5
Chlorine binding site 1 out
of 1 in the Human Carbonic Anhydrase II in Complex with 2-(3-Chloro-4- Hydroxyphenyl)-N-(4-Sulfamoylphenethyl)Acetamide
Mono view Stereo pair view
Reference:
R.A.Davis,
A.Hofmann,
A.Osman,
R.A.Hall,
F.A.Muhlschlegel,
D.Vullo,
A.Innocenti,
C.T.Supuran,
S.A.Poulsen.
Natural Product-Based Phenols As Novel Probes For Mycobacterial and Fungal Carbonic Anhydrases J.Med.Chem. V. 54 1682 2011.
Page generated: Sat Dec 12 09:57:19 2020
ISSN: ISSN 0022-2623 PubMed: 21332115 DOI: 10.1021/JM1013242 |
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