Atomistry » Chlorine » PDB 4da0-4dhm » 4dfw
Atomistry »
  Chlorine »
    PDB 4da0-4dhm »
      4dfw »

Chlorine in PDB 4dfw: Oxime-Based Post Solid-Phase Peptide Diversification: Identification of High Affinity Polo-Like Kinase 1 (PLK1) Polo-Box Domain Binding Peptides

Enzymatic activity of Oxime-Based Post Solid-Phase Peptide Diversification: Identification of High Affinity Polo-Like Kinase 1 (PLK1) Polo-Box Domain Binding Peptides

All present enzymatic activity of Oxime-Based Post Solid-Phase Peptide Diversification: Identification of High Affinity Polo-Like Kinase 1 (PLK1) Polo-Box Domain Binding Peptides:
2.7.11.21;

Protein crystallography data

The structure of Oxime-Based Post Solid-Phase Peptide Diversification: Identification of High Affinity Polo-Like Kinase 1 (PLK1) Polo-Box Domain Binding Peptides, PDB code: 4dfw was solved by F.Liu, J.-E.Park, W.-J.Qian, D.Lim, M.Gr Ber, T.Berg, M.B.Yaffe, K.S.Lee, T.R.Burke Jr., with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 13.86 / 1.55
Space group P 1
Cell size a, b, c (Å), α, β, γ (°) 35.665, 34.844, 47.097, 76.44, 86.95, 69.14
R / Rfree (%) 15.5 / 19.6

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Oxime-Based Post Solid-Phase Peptide Diversification: Identification of High Affinity Polo-Like Kinase 1 (PLK1) Polo-Box Domain Binding Peptides (pdb code 4dfw). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Oxime-Based Post Solid-Phase Peptide Diversification: Identification of High Affinity Polo-Like Kinase 1 (PLK1) Polo-Box Domain Binding Peptides, PDB code: 4dfw:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 4dfw

Go back to Chlorine Binding Sites List in 4dfw
Chlorine binding site 1 out of 2 in the Oxime-Based Post Solid-Phase Peptide Diversification: Identification of High Affinity Polo-Like Kinase 1 (PLK1) Polo-Box Domain Binding Peptides


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Oxime-Based Post Solid-Phase Peptide Diversification: Identification of High Affinity Polo-Like Kinase 1 (PLK1) Polo-Box Domain Binding Peptides within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl701

b:16.0
occ:1.00
 H A:SER390 2.4 3.6 1.0
HA A:LYS388 2.9 70.1 1.0
OG A:SER390 2.9 13.3 1.0
O A:HOH824 3.0 11.4 1.0
HG3 A:GLU391 3.0 41.1 1.0
HD2 A:PRO389 3.1 1.1 1.0
N A:SER390 3.2 12.6 1.0
HG A:SER390 3.3 57.5 1.0
HB2 A:ALA577 3.3 11.0 1.0
C A:LYS388 3.3 12.2 1.0
N A:PRO389 3.5 11.3 1.0
CA A:LYS388 3.5 12.1 1.0
H A:GLU391 3.5 0.0 1.0
HB3 A:LYS388 3.5 8.0 1.0
HD3 A:LYS388 3.6 0.1 1.0
HD2 A:LYS388 3.7 0.0 1.0
CD A:PRO389 3.7 10.9 1.0
HH11 A:ARG581 3.7 76.5 1.0
O A:LYS388 3.8 14.1 1.0
CB A:SER390 3.8 12.7 1.0
HH12 A:ARG581 3.9 0.0 1.0
CA A:SER390 3.9 11.0 1.0
HG2 A:PRO389 3.9 3.6 1.0
HB3 A:SER390 3.9 1.2 1.0
N A:GLU391 4.0 12.6 1.0
CB A:LYS388 4.0 14.2 1.0
CG A:GLU391 4.0 20.1 1.0
CB A:ALA577 4.0 12.8 1.0
CD A:LYS388 4.0 37.4 1.0
NH1 A:ARG581 4.1 11.3 1.0
HB3 A:ALA577 4.1 9.4 1.0
HB1 A:ALA577 4.1 66.2 1.0
C A:PRO389 4.3 11.3 1.0
C A:SER390 4.3 13.2 1.0
HB2 A:GLU391 4.4 14.6 1.0
O A:HOH837 4.4 20.2 1.0
OE2 A:GLU391 4.4 30.5 1.0
CG A:PRO389 4.4 10.3 1.0
CA A:PRO389 4.4 10.4 1.0
CD A:GLU391 4.5 24.7 1.0
HD3 A:PRO389 4.5 9.2 1.0
O A:HOH834 4.6 18.6 1.0
HG2 A:GLU391 4.6 13.5 1.0
CB A:GLU391 4.6 20.7 1.0
CG A:LYS388 4.7 17.9 1.0
HB2 A:SER390 4.7 3.3 1.0
N A:LYS388 4.8 12.8 1.0
HB2 A:LYS388 4.8 4.2 1.0
HA A:SER390 4.8 0.0 1.0
O A:HOH810 4.9 10.1 1.0
CA A:GLU391 4.9 18.2 1.0
O A:HOH1033 4.9 29.8 1.0
H A:LYS388 4.9 19.9 1.0
HZ3 A:LYS388 5.0 26.3 1.0

Chlorine binding site 2 out of 2 in 4dfw

Go back to Chlorine Binding Sites List in 4dfw
Chlorine binding site 2 out of 2 in the Oxime-Based Post Solid-Phase Peptide Diversification: Identification of High Affinity Polo-Like Kinase 1 (PLK1) Polo-Box Domain Binding Peptides


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Oxime-Based Post Solid-Phase Peptide Diversification: Identification of High Affinity Polo-Like Kinase 1 (PLK1) Polo-Box Domain Binding Peptides within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl702

b:19.6
occ:1.00
 H A:THR561 2.3 67.0 1.0
O A:HOH1014 2.9 28.0 1.0
HA A:ARG560 2.9 4.5 1.0
O A:HOH876 3.1 16.1 1.0
O A:HOH847 3.1 26.5 1.0
N A:THR561 3.2 7.8 1.0
HB3 A:GLU401 3.2 21.1 1.0
HA A:PRO403 3.3 84.2 1.0
HD2 A:ARG560 3.3 22.5 1.0
HB3 A:PRO403 3.4 11.5 1.0
HG3 A:PRO403 3.5 0.5 1.0
HD3 A:ARG560 3.5 88.1 1.0
CA A:ARG560 3.7 8.8 1.0
HB3 A:ARG560 3.7 5.1 1.0
HB A:THR561 3.7 89.4 1.0
O A:THR561 3.8 9.8 1.0
CA A:PRO403 3.9 17.6 1.0
CD A:ARG560 3.9 16.8 1.0
C A:ARG560 3.9 8.1 1.0
CB A:PRO403 3.9 20.5 1.0
N A:PRO403 3.9 18.2 1.0
HG2 A:GLU401 4.0 6.0 1.0
H A:ASP402 4.0 11.8 1.0
CG A:PRO403 4.1 22.8 1.0
CA A:THR561 4.1 7.9 1.0
CB A:GLU401 4.1 11.7 1.0
HD3 A:PRO403 4.1 26.3 1.0
CB A:ARG560 4.2 13.6 1.0
CB A:THR561 4.3 9.2 1.0
CD A:PRO403 4.3 24.0 1.0
HG1 A:THR561 4.3 0.0 1.0
OE1 A:GLU401 4.4 25.5 1.0
CG A:GLU401 4.4 11.3 1.0
C A:THR561 4.4 9.1 1.0
N A:ASP402 4.5 14.0 1.0
C A:ASP402 4.5 16.5 1.0
HA A:GLU401 4.6 0.0 1.0
CD A:GLU401 4.6 20.5 1.0
CG A:ARG560 4.7 17.2 1.0
O A:PHE559 4.7 11.1 1.0
OG1 A:THR561 4.7 9.6 1.0
O A:HOH906 4.7 27.0 1.0
HB2 A:GLU401 4.8 20.9 1.0
CA A:GLU401 4.8 12.4 1.0
N A:ARG560 4.9 10.1 1.0
HB2 A:PRO403 4.9 22.5 1.0
O A:HOH823 4.9 18.0 1.0
HG2 A:PRO403 5.0 11.8 1.0
O A:ASP402 5.0 18.6 1.0
HA A:THR561 5.0 0.6 1.0

Reference:

F.Liu, J.-E.Park, W.-J.Qian, D.Lim, A.Scharow, T.Berg, M.B.Yaffe, K.S.Lee, T.R.Burke. Oxime-Based Post Solid-Phase Peptide Diversification: Identification of High Affinity Polo-Like Kinase 1 (PLK1) Polo-Box Domain Binding Peptides Chem.Biol. 2012.
ISSN: ISSN 1074-5521
PubMed: 22292814
Page generated: Sat Dec 12 10:32:00 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy