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Atomistry » Chlorine » PDB 4qyy-4r66 » 4qz0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 4qyy-4r66 » 4qz0 » |
Chlorine in PDB 4qz0: Ycp BETA5-M45V Mutant in Complex with the Epoxyketone Inhibitor Onx 0914Enzymatic activity of Ycp BETA5-M45V Mutant in Complex with the Epoxyketone Inhibitor Onx 0914
All present enzymatic activity of Ycp BETA5-M45V Mutant in Complex with the Epoxyketone Inhibitor Onx 0914:
3.4.25.1; Protein crystallography data
The structure of Ycp BETA5-M45V Mutant in Complex with the Epoxyketone Inhibitor Onx 0914, PDB code: 4qz0
was solved by
E.M.Huber,
W.Heinemeyer,
M.Groll,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4qz0:
The structure of Ycp BETA5-M45V Mutant in Complex with the Epoxyketone Inhibitor Onx 0914 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Ycp BETA5-M45V Mutant in Complex with the Epoxyketone Inhibitor Onx 0914
(pdb code 4qz0). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Ycp BETA5-M45V Mutant in Complex with the Epoxyketone Inhibitor Onx 0914, PDB code: 4qz0: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 4qz0Go back to Chlorine Binding Sites List in 4qz0
Chlorine binding site 1 out
of 2 in the Ycp BETA5-M45V Mutant in Complex with the Epoxyketone Inhibitor Onx 0914
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 4qz0Go back to Chlorine Binding Sites List in 4qz0
Chlorine binding site 2 out
of 2 in the Ycp BETA5-M45V Mutant in Complex with the Epoxyketone Inhibitor Onx 0914
Mono view Stereo pair view
Reference:
E.M.Huber,
W.Heinemeyer,
M.Groll.
Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and Onx 0914. Structure 2015.
Page generated: Sat Dec 12 11:09:49 2020
ISSN: ISSN 0969-2126 PubMed: 25599643 DOI: 10.1016/J.STR.2014.11.019 |
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