Chlorine in PDB 4x97: Crystal Structure of Lysosomal Phospholipase A2 in Complex with Methyl Arachidonyl Fluorophosphonate (Mafp)

The structure of Crystal Structure of Lysosomal Phospholipase A2 in Complex with Methyl Arachidonyl Fluorophosphonate (Mafp), PDB code: 4x97 was solved by A.Glukhova, J.J.G.Tesmer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.65
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	69.147, 85.495, 88.852, 88.85, 70.87, 79.74
R / Rfree (%)	17.9 / 21.9

The binding sites of Chlorine atom in the Crystal Structure of Lysosomal Phospholipase A2 in Complex with Methyl Arachidonyl Fluorophosphonate (Mafp) (pdb code 4x97). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Lysosomal Phospholipase A2 in Complex with Methyl Arachidonyl Fluorophosphonate (Mafp), PDB code: 4x97:

Chlorine binding site 1 out of 1 in the Crystal Structure of Lysosomal Phospholipase A2 in Complex with Methyl Arachidonyl Fluorophosphonate (Mafp)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Lysosomal Phospholipase A2 in Complex with Methyl Arachidonyl Fluorophosphonate (Mafp) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl407 b:41.4 occ:1.00 NE2 B:GLN294 3.3 33.7 1.0 N B:GLN348 3.4 35.6 1.0 CB B:GLN294 3.8 31.1 1.0 CD2 B:HIS347 3.8 32.0 1.0 CA B:HIS347 3.9 36.0 1.0 CB B:GLN348 4.0 39.5 1.0 CB B:HIS347 4.1 33.8 1.0 C B:HIS347 4.2 34.7 1.0 CG B:GLN294 4.2 31.7 1.0 CD B:GLN294 4.2 32.4 1.0 CG B:HIS347 4.2 34.0 1.0 CA B:GLN348 4.3 37.1 1.0 CA B:GLN294 4.4 31.5 1.0 CG B:GLN348 4.5 44.6 1.0 OE1 B:GLN348 4.8 52.6 1.0 N B:GLN294 4.9 31.2 1.0 NE2 B:HIS347 4.9 32.9 1.0 O B:GLN348 5.0 34.9 1.0

A.Glukhova, V.Hinkovska-Galcheva, R.Kelly, A.Abe, J.A.Shayman, J.J.G.Tesmer. Structure and Function of Lysosomal Phospholipase A2 and Lecithin:Cholesterol Acyltransferase Nat Commun 2015.
ISSN: ESSN 2041-1723
DOI: 10.1038/NCOMMS7250