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Chlorine in PDB 5l7f: Crystal Structure of MMP12 Mutant K421A in Complex with RXP470.1 Conjugated with Fluorophore CY5,5 in Space Group P21.
Enzymatic activity of Crystal Structure of MMP12 Mutant K421A in Complex with RXP470.1 Conjugated with Fluorophore CY5,5 in Space Group P21.
All present enzymatic activity of Crystal Structure of MMP12 Mutant K421A in Complex with RXP470.1 Conjugated with Fluorophore CY5,5 in Space Group P21.:
3.4.24.65;
3.4.24.65;
Protein crystallography data
The structure of Crystal Structure of MMP12 Mutant K421A in Complex with RXP470.1 Conjugated with Fluorophore CY5,5 in Space Group P21., PDB code: 5l7f
was solved by
L.Tepshi,
T.Bordenave,
C.Rouanet-Mehouas,
L.Devel,
V.Dive,
E.A.Stura,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 47.34 / 1.80 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 48.920, 70.370, 52.220, 90.00, 104.61, 90.00 |
| R / Rfree (%) | 17.6 / 19.5 |
Other elements in 5l7f:
The structure of Crystal Structure of MMP12 Mutant K421A in Complex with RXP470.1 Conjugated with Fluorophore CY5,5 in Space Group P21. also contains other interesting chemical elements:
| Zinc | (Zn) | 4 atoms |
| Bromine | (Br) | 3 atoms |
| Calcium | (Ca) | 6 atoms |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of MMP12 Mutant K421A in Complex with RXP470.1 Conjugated with Fluorophore CY5,5 in Space Group P21.
(pdb code 5l7f). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of MMP12 Mutant K421A in Complex with RXP470.1 Conjugated with Fluorophore CY5,5 in Space Group P21., PDB code: 5l7f:
Jump to Chlorine binding site number: 1; 2;
In total 2 binding sites of Chlorine where determined in the Crystal Structure of MMP12 Mutant K421A in Complex with RXP470.1 Conjugated with Fluorophore CY5,5 in Space Group P21., PDB code: 5l7f:
Jump to Chlorine binding site number: 1; 2;
Chlorine binding site 1 out of 2 in 5l7f
Go back to
Chlorine Binding Sites List in 5l7f
Chlorine binding site 1 out
of 2 in the Crystal Structure of MMP12 Mutant K421A in Complex with RXP470.1 Conjugated with Fluorophore CY5,5 in Space Group P21.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Crystal Structure of MMP12 Mutant K421A in Complex with RXP470.1 Conjugated with Fluorophore CY5,5 in Space Group P21. within 5.0Å range:
|
Chlorine binding site 2 out of 2 in 5l7f
Go back to
Chlorine Binding Sites List in 5l7f
Chlorine binding site 2 out
of 2 in the Crystal Structure of MMP12 Mutant K421A in Complex with RXP470.1 Conjugated with Fluorophore CY5,5 in Space Group P21.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Crystal Structure of MMP12 Mutant K421A in Complex with RXP470.1 Conjugated with Fluorophore CY5,5 in Space Group P21. within 5.0Å range:
|
Reference:
T.Bordenave,
M.Helle,
F.Beau,
D.Georgiadis,
L.Tepshi,
M.Bernes,
Y.Ye,
L.Levenez,
E.Poquet,
H.Nozach,
M.Razavian,
J.Toczek,
E.A.Stura,
V.Dive,
M.M.Sadeghi,
L.Devel.
Synthesis and in Vitro and in Vivo Evaluation of Mmp-12 Selective Optical Probes. Bioconjug.Chem. V. 27 2407 2016.
ISSN: ISSN 1043-1802
PubMed: 27564088
DOI: 10.1021/ACS.BIOCONJCHEM.6B00377
Page generated: Fri Jul 26 11:15:19 2024
ISSN: ISSN 1043-1802
PubMed: 27564088
DOI: 10.1021/ACS.BIOCONJCHEM.6B00377
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