Chlorine in PDB 5u09: High-Resolution Crystal Structure of the Human CB1 Cannabinoid Receptor

The structure of High-Resolution Crystal Structure of the Human CB1 Cannabinoid Receptor, PDB code: 5u09 was solved by Z.H.Shao, J.Yin, D.Rosenbaum, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.01 / 2.60
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	50.652, 80.381, 81.178, 90.00, 91.72, 90.00
R / Rfree (%)	18 / 23.8

The structure of High-Resolution Crystal Structure of the Human CB1 Cannabinoid Receptor also contains other interesting chemical elements:

Fluorine

(F)

3 atoms

The binding sites of Chlorine atom in the High-Resolution Crystal Structure of the Human CB1 Cannabinoid Receptor (pdb code 5u09). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the High-Resolution Crystal Structure of the Human CB1 Cannabinoid Receptor, PDB code: 5u09:

Chlorine binding site 1 out of 1 in the High-Resolution Crystal Structure of the Human CB1 Cannabinoid Receptor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of High-Resolution Crystal Structure of the Human CB1 Cannabinoid Receptor within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1210 b:57.9 occ:1.00 CLAA A:7DY1210 0.0 57.9 1.0 CBC A:7DY1210 1.7 48.1 1.0 CBB A:7DY1210 2.7 46.7 1.0 CBA A:7DY1210 2.7 46.4 1.0 CH2 A:TRP279 3.4 49.7 1.0 CZ3 A:TRP356 3.8 30.2 1.0 CG1 A:VAL196 3.9 41.7 1.0 CAW A:7DY1210 4.0 48.2 1.0 CAV A:7DY1210 4.0 43.5 1.0 CZ3 A:TRP279 4.0 45.6 1.0 CZ2 A:TRP279 4.3 43.6 1.0 CG2 A:THR197 4.4 39.9 1.0 CAO A:7DY1210 4.5 46.6 1.0 N A:THR197 4.5 33.0 1.0 CH2 A:TRP356 4.6 34.4 1.0 CB A:VAL196 4.6 39.2 1.0 CD2 A:LEU359 4.6 50.9 1.0 CE3 A:TRP356 4.6 28.8 1.0 CA A:THR197 4.7 39.4 1.0 C A:VAL196 4.8 32.1 1.0 CD1 A:LEU193 4.9 38.3 1.0 CE A:MET363 4.9 58.3 1.0

Z.Shao, J.Yin, K.Chapman, M.Grzemska, L.Clark, J.Wang, D.M.Rosenbaum. High-Resolution Crystal Structure of the Human CB1 Cannabinoid Receptor. Nature 2016.
ISSN: ESSN 1476-4687
PubMed: 27851727
DOI: 10.1038/NATURE20613