Chlorine in PDB 5zkn: Structure of N-Acetylmannosamine-6-Phosphate 2-Epimerase From Fusobacterium Nucleatum

All present enzymatic activity of Structure of N-Acetylmannosamine-6-Phosphate 2-Epimerase From Fusobacterium Nucleatum:
5.1.3.9;

The structure of Structure of N-Acetylmannosamine-6-Phosphate 2-Epimerase From Fusobacterium Nucleatum, PDB code: 5zkn was solved by L.Manjunath, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.82 / 2.21
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	47.515, 75.347, 135.882, 90.00, 90.00, 90.00
R / Rfree (%)	18.3 / 23.3

The binding sites of Chlorine atom in the Structure of N-Acetylmannosamine-6-Phosphate 2-Epimerase From Fusobacterium Nucleatum (pdb code 5zkn). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of N-Acetylmannosamine-6-Phosphate 2-Epimerase From Fusobacterium Nucleatum, PDB code: 5zkn:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structure of N-Acetylmannosamine-6-Phosphate 2-Epimerase From Fusobacterium Nucleatum


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of N-Acetylmannosamine-6-Phosphate 2-Epimerase From Fusobacterium Nucleatum within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl301 b:66.2 occ:1.00 NZ A:LYS69 3.1 47.0 1.0 NH2 A:ARG46 3.2 46.3 1.0 NE2 A:GLN17 3.3 50.8 1.0 CE A:LYS69 3.4 55.1 1.0 NE A:ARG46 3.4 45.2 1.0 CD1 A:ILE67 3.7 39.4 1.0 CZ A:ARG46 3.7 48.6 1.0 OE1 A:GLN17 4.0 53.8 1.0 CD A:GLN17 4.1 52.1 1.0 OE2 A:GLU183 4.1 58.9 1.0 O A:HOH419 4.1 61.4 1.0 CG2 A:THR152 4.3 43.1 1.0 CL A:CL302 4.4 95.4 1.0 CD1 A:ILE79 4.4 64.7 1.0 CD A:ARG46 4.6 44.5 1.0 CD A:LYS69 4.8 55.5 1.0 NH1 A:ARG46 5.0 44.7 1.0

Chlorine binding site 2 out of 2 in the Structure of N-Acetylmannosamine-6-Phosphate 2-Epimerase From Fusobacterium Nucleatum


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of N-Acetylmannosamine-6-Phosphate 2-Epimerase From Fusobacterium Nucleatum within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl302 b:95.4 occ:1.00 OH A:TYR78 3.4 92.0 1.0 CD2 A:LEU153 4.3 64.0 1.0 CL A:CL301 4.4 66.2 1.0 NZ A:LYS69 4.5 47.0 1.0 CD1 A:ILE79 4.5 64.7 1.0 CZ A:TYR78 4.6 94.9 1.0 CE A:LYS69 4.7 55.1 1.0 CG2 A:THR152 4.7 43.1 1.0 O A:THR152 4.7 59.7 1.0 CE2 A:TYR156 4.8 60.5 1.0 CZ A:TYR156 4.8 62.8 1.0 O A:HOH419 4.8 61.4 1.0 CD2 A:TYR156 4.9 67.1 1.0 CE1 A:TYR156 4.9 59.9 1.0

L.Manjunath, S.R.Guntupalli, M.J.Currie, R.A.North, R.C.J.Dobson, V.Nayak, R.Subramanian. Crystal Structures and Kinetic Analyses of N-Acetylmannosamine-6-Phosphate 2-Epimerases From Fusobacterium Nucleatum and Vibrio Cholerae Acta Crystallogr F Struct V. 74 431 2018BIOL Commun.
ISSN: ESSN 2053-230X
PubMed: 29969107
DOI: 10.1107/S2053230X18008543