Atomistry » Chlorine » PDB 6fkv-6frm » 6fkv
Atomistry »
  Chlorine »
    PDB 6fkv-6frm »
      6fkv »

Chlorine in PDB 6fkv: Structure and Function of Aldehyde Dehydrogenase From Thermus Thermophilus: An Enzyme with An Evolutionarily-Distinct C-Terminal Arm (Recombinant Protein with Shortened C-Terminal, ADH508)

Enzymatic activity of Structure and Function of Aldehyde Dehydrogenase From Thermus Thermophilus: An Enzyme with An Evolutionarily-Distinct C-Terminal Arm (Recombinant Protein with Shortened C-Terminal, ADH508)

All present enzymatic activity of Structure and Function of Aldehyde Dehydrogenase From Thermus Thermophilus: An Enzyme with An Evolutionarily-Distinct C-Terminal Arm (Recombinant Protein with Shortened C-Terminal, ADH508):
1.2.1.3;

Protein crystallography data

The structure of Structure and Function of Aldehyde Dehydrogenase From Thermus Thermophilus: An Enzyme with An Evolutionarily-Distinct C-Terminal Arm (Recombinant Protein with Shortened C-Terminal, ADH508), PDB code: 6fkv was solved by K.A.Hayes, M.R.Noor, A.Djeghader, T.Soulimane, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 48.04 / 2.90
Space group P 41 21 2
Cell size a, b, c (Å), α, β, γ (°) 105.190, 105.190, 314.570, 90.00, 90.00, 90.00
R / Rfree (%) 19 / 22.9

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Structure and Function of Aldehyde Dehydrogenase From Thermus Thermophilus: An Enzyme with An Evolutionarily-Distinct C-Terminal Arm (Recombinant Protein with Shortened C-Terminal, ADH508) (pdb code 6fkv). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Structure and Function of Aldehyde Dehydrogenase From Thermus Thermophilus: An Enzyme with An Evolutionarily-Distinct C-Terminal Arm (Recombinant Protein with Shortened C-Terminal, ADH508), PDB code: 6fkv:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in 6fkv

Go back to Chlorine Binding Sites List in 6fkv
Chlorine binding site 1 out of 4 in the Structure and Function of Aldehyde Dehydrogenase From Thermus Thermophilus: An Enzyme with An Evolutionarily-Distinct C-Terminal Arm (Recombinant Protein with Shortened C-Terminal, ADH508)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure and Function of Aldehyde Dehydrogenase From Thermus Thermophilus: An Enzyme with An Evolutionarily-Distinct C-Terminal Arm (Recombinant Protein with Shortened C-Terminal, ADH508) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl607

b:63.2
occ:1.00
 NH1 A:ARG342 3.1 75.4 1.0
NH2 A:ARG346 3.3 58.9 1.0
NH1 A:ARG346 3.3 65.0 1.0
CB A:SER240 3.7 59.4 1.0
OG A:SER240 3.7 63.8 1.0
CZ A:ARG346 3.8 64.1 1.0
CD A:ARG342 4.2 78.8 1.0
CZ A:ARG342 4.2 81.2 1.0
NE A:ARG342 4.6 78.6 1.0
N A:SER240 4.7 51.8 1.0
CA A:SER240 4.8 53.5 1.0
O1 A:PEG602 4.9 74.0 1.0
CG A:ARG342 5.0 66.5 1.0

Chlorine binding site 2 out of 4 in 6fkv

Go back to Chlorine Binding Sites List in 6fkv
Chlorine binding site 2 out of 4 in the Structure and Function of Aldehyde Dehydrogenase From Thermus Thermophilus: An Enzyme with An Evolutionarily-Distinct C-Terminal Arm (Recombinant Protein with Shortened C-Terminal, ADH508)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure and Function of Aldehyde Dehydrogenase From Thermus Thermophilus: An Enzyme with An Evolutionarily-Distinct C-Terminal Arm (Recombinant Protein with Shortened C-Terminal, ADH508) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl608

b:60.0
occ:1.00
 CB A:ARG342 3.6 56.2 1.0
N A:ARG342 3.7 51.2 1.0
NE A:ARG342 3.9 78.6 1.0
N A:GLU341 4.1 59.6 1.0
CB A:GLU341 4.2 65.4 1.0
CB A:ASN340 4.2 52.6 1.0
CA A:ARG342 4.4 50.2 1.0
CA A:GLU341 4.5 58.0 1.0
NH2 A:ARG342 4.5 87.4 1.0
CG A:ASN340 4.5 54.1 1.0
OD1 A:ASN340 4.6 53.3 1.0
C A:GLU341 4.6 54.2 1.0
CZ A:ARG342 4.7 81.2 1.0
CD A:ARG342 4.7 78.8 1.0
CG A:ARG342 4.8 66.5 1.0
C A:ASN340 5.0 54.5 1.0

Chlorine binding site 3 out of 4 in 6fkv

Go back to Chlorine Binding Sites List in 6fkv
Chlorine binding site 3 out of 4 in the Structure and Function of Aldehyde Dehydrogenase From Thermus Thermophilus: An Enzyme with An Evolutionarily-Distinct C-Terminal Arm (Recombinant Protein with Shortened C-Terminal, ADH508)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure and Function of Aldehyde Dehydrogenase From Thermus Thermophilus: An Enzyme with An Evolutionarily-Distinct C-Terminal Arm (Recombinant Protein with Shortened C-Terminal, ADH508) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl609

b:67.5
occ:1.00
 NH1 A:ARG360 3.6 96.0 1.0
O A:GLU393 4.0 52.5 1.0
CB A:GLU393 4.0 54.9 1.0
C A:GLU393 4.1 50.2 1.0
N A:VAL394 4.2 44.8 1.0
NH2 A:ARG395 4.3 68.0 1.0
C A:VAL394 4.5 47.7 1.0
CA A:VAL394 4.5 45.9 1.0
CA A:GLU393 4.7 52.4 1.0
N A:ARG395 4.7 51.1 1.0
CZ A:ARG360 4.8 97.8 1.0
CZ A:ARG395 4.8 79.8 1.0
O A:VAL394 4.9 46.6 1.0
CB A:ARG360 5.0 65.3 1.0
N A:ARG360 5.0 50.0 1.0

Chlorine binding site 4 out of 4 in 6fkv

Go back to Chlorine Binding Sites List in 6fkv
Chlorine binding site 4 out of 4 in the Structure and Function of Aldehyde Dehydrogenase From Thermus Thermophilus: An Enzyme with An Evolutionarily-Distinct C-Terminal Arm (Recombinant Protein with Shortened C-Terminal, ADH508)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Structure and Function of Aldehyde Dehydrogenase From Thermus Thermophilus: An Enzyme with An Evolutionarily-Distinct C-Terminal Arm (Recombinant Protein with Shortened C-Terminal, ADH508) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl610

b:66.5
occ:1.00
 O A:HOH703 2.7 27.4 1.0
NH2 A:ARG342 3.1 87.4 1.0
OG A:SER184 3.1 49.7 1.0
OD2 A:ASP186 3.7 75.8 1.0
CB A:SER184 4.0 49.5 1.0
CZ A:ARG342 4.1 81.2 1.0
CA A:SER184 4.2 49.2 1.0
NH1 A:ARG342 4.4 75.4 1.0
OE2 A:GLU185 4.5 95.3 1.0
CG A:ASP186 4.5 69.1 1.0
N A:GLU185 4.6 61.9 1.0
CG A:GLU185 4.7 72.7 1.0
OD1 A:ASP186 4.9 66.0 1.0
C A:SER184 4.9 56.5 1.0
CA A:ALA157 5.0 45.4 1.0
ND2 A:ASN340 5.0 58.7 1.0

Reference:

K.Hayes, M.Noor, A.Djeghader, P.Armshaw, T.Pembroke, S.Tofail, T.Soulimane. The Quaternary Structure of Thermus Thermophilus Aldehyde Dehydrogenase Is Stabilized By An Evolutionary Distinct C-Terminal Arm Extension. Sci Rep V. 8 13327 2018.
ISSN: ESSN 2045-2322
PubMed: 30190503
DOI: 10.1038/S41598-018-31724-8
Page generated: Sat Jul 27 23:21:04 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy