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Chlorine in PDB 6i6c: Sepiapterin Reductase in Complex with Compound 2Enzymatic activity of Sepiapterin Reductase in Complex with Compound 2
All present enzymatic activity of Sepiapterin Reductase in Complex with Compound 2:
1.1.1.153; Protein crystallography data
The structure of Sepiapterin Reductase in Complex with Compound 2, PDB code: 6i6c
was solved by
J.Alen,
M.Schade,
M.Wagener,
M.Blaesse,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Sepiapterin Reductase in Complex with Compound 2
(pdb code 6i6c). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Sepiapterin Reductase in Complex with Compound 2, PDB code: 6i6c: Jump to Chlorine binding site number: 1; 2; 3; Chlorine binding site 1 out of 3 in 6i6cGo back to Chlorine Binding Sites List in 6i6c
Chlorine binding site 1 out
of 3 in the Sepiapterin Reductase in Complex with Compound 2
Mono view Stereo pair view
Chlorine binding site 2 out of 3 in 6i6cGo back to Chlorine Binding Sites List in 6i6c
Chlorine binding site 2 out
of 3 in the Sepiapterin Reductase in Complex with Compound 2
Mono view Stereo pair view
Chlorine binding site 3 out of 3 in 6i6cGo back to Chlorine Binding Sites List in 6i6c
Chlorine binding site 3 out
of 3 in the Sepiapterin Reductase in Complex with Compound 2
Mono view Stereo pair view
Reference:
J.Alen,
M.Schade,
M.Wagener,
F.Christian,
S.Nordhoff,
B.Merla,
T.R.Dunkern,
G.Bahrenberg,
P.Ratcliffe.
Fragment-Based Discovery of Novel Potent Sepiapterin Reductase Inhibitors. J.Med.Chem. V. 62 6391 2019.
Page generated: Sat Dec 12 13:09:50 2020
ISSN: ISSN 0022-2623 PubMed: 31244106 DOI: 10.1021/ACS.JMEDCHEM.9B00218 |
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