Chlorine in PDB 6v2v: Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and PD0325901

Enzymatic activity of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and PD0325901

All present enzymatic activity of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and PD0325901:
2.7.11.1; 2.7.12.2;

Protein crystallography data

The structure of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and PD0325901, PDB code: 6v2v was solved by K.Li, G.Gonzalez Del-Pino, E.Park, M.J.Eck, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 43.57 / 2.47
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 116.527, 116.527, 130.712, 90.00, 90.00, 120.00
R / Rfree (%) 18.3 / 21.3

Other elements in 6v2v:

The structure of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and PD0325901 also contains other interesting chemical elements:

Fluorine (F) 3 atoms
Magnesium (Mg) 2 atoms
Iodine (I) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and PD0325901 (pdb code 6v2v). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and PD0325901, PDB code: 6v2v:

Chlorine binding site 1 out of 1 in 6v2v

Go back to Chlorine Binding Sites List in 6v2v
Chlorine binding site 1 out of 1 in the Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and PD0325901


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and PD0325901 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl803

b:82.0
occ:1.00
CZ A:TYR472 4.1 46.1 1.0
OH A:TYR472 4.1 55.5 1.0
CE2 A:TYR472 4.2 44.4 1.0
OE1 A:GLN524 4.3 67.8 1.0
CE A:MET484 4.4 48.7 1.0
CG1 A:VAL459 4.5 50.5 1.0
CE1 A:TYR472 4.6 41.4 1.0
CD2 A:TYR472 4.8 48.6 1.0

Reference:

K.Li, G.Gonzalez Del-Pino, E.Park, M.J.Eck. Crystal Structure of the Braf:MEK1 Kinases in Complex with Amppnp and PD0325901 To Be Published.
Page generated: Sat Dec 12 14:12:10 2020

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