Chlorine in PDB 7c15: Crystal Structure of A Dinucleotide-Binding Protein (Q274A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho-Guanosine (Form II)

The structure of Crystal Structure of A Dinucleotide-Binding Protein (Q274A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho-Guanosine (Form II), PDB code: 7c15 was solved by S.P.Kanaujia, M.Chandravanshi, R.Samanta, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	57.73 / 1.80
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	57.73, 102.56, 66.18, 90, 90.09, 90
R / Rfree (%)	16.1 / 20.9

The binding sites of Chlorine atom in the Crystal Structure of A Dinucleotide-Binding Protein (Q274A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho-Guanosine (Form II) (pdb code 7c15). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of A Dinucleotide-Binding Protein (Q274A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho-Guanosine (Form II), PDB code: 7c15:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Crystal Structure of A Dinucleotide-Binding Protein (Q274A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho-Guanosine (Form II)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of A Dinucleotide-Binding Protein (Q274A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho-Guanosine (Form II) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl501 b:55.8 occ:1.00 O A:HOH838 2.8 29.7 1.0 N A:GLY26 3.1 17.7 1.0 CA A:GLY26 3.8 18.6 1.0 O A:HOH726 4.0 21.2 1.0 C A:GLY25 4.1 18.1 1.0 CA A:GLY25 4.1 17.7 1.0 O A:HOH604 4.5 35.2 1.0

Chlorine binding site 2 out of 3 in the Crystal Structure of A Dinucleotide-Binding Protein (Q274A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho-Guanosine (Form II)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of A Dinucleotide-Binding Protein (Q274A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho-Guanosine (Form II) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl502 b:50.8 occ:1.00 O1 A:EDO507 2.5 30.2 1.0 C2 A:EDO507 3.3 22.8 1.0 C1 A:EDO507 3.4 24.7 1.0 O10 A:FGO509 3.9 34.8 1.0 O3 A:CO3506 4.0 40.6 1.0 CE1 A:PHE361 4.0 16.7 1.0 CD1 A:PHE361 4.0 17.0 1.0 O A:HOH678 4.0 29.9 1.0 CB A:ASP173 4.1 14.9 1.0 NZ A:LYS369 4.1 16.8 0.5 O1 A:CO3506 4.1 43.0 1.0 OD2 A:ASP173 4.2 18.3 1.0 NZ A:LYS369 4.3 15.7 0.5 O A:HOH694 4.3 20.7 1.0 C A:CO3506 4.5 41.9 1.0 O2 A:EDO507 4.5 24.1 1.0 CG A:ASP173 4.7 14.7 1.0 CE A:LYS369 4.8 17.0 0.5 C21 A:FGO509 4.9 17.0 1.0 C20 A:FGO509 5.0 19.6 1.0 CE A:LYS369 5.0 16.0 0.5

Chlorine binding site 3 out of 3 in the Crystal Structure of A Dinucleotide-Binding Protein (Q274A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho-Guanosine (Form II)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of A Dinucleotide-Binding Protein (Q274A) of Abc Transporter Endogenously Bound to Uridylyl-3'-5'-Phospho-Guanosine (Form II) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl501 b:53.5 occ:1.00 O B:HOH667 2.4 37.3 1.0 OE1 B:GLU214 3.1 26.5 1.0 NZ B:LYS157 3.7 18.8 1.0 OE2 B:GLU214 3.7 24.0 1.0 CD B:GLU214 3.9 23.2 1.0 CE B:LYS157 4.0 16.6 1.0 O B:HOH642 4.1 32.9 1.0 CG1 B:VAL153 4.1 17.8 1.0 CZ2 B:TRP216 4.3 18.4 1.0 CD1 B:LEU207 4.3 19.9 1.0 NE1 B:TRP216 4.4 18.8 1.0 CE2 B:TRP216 4.7 16.7 1.0 CB B:ASN210 4.7 17.0 1.0

M.Chandravanshi, R.Samanta, S.P.Kanaujia. Structural and Thermodynamic Insights Into the Novel Dinucleotide-Binding Protein of Abc Transporter Unveils Its Moonlighting Function. Febs J. 2021.
ISSN: ISSN 1742-464X
PubMed: 33599038
DOI: 10.1111/FEBS.15774