Chlorine in PDB 7jib: Room Temperature Crystal Structure of NSP10/NSP16 From Sars-Cov-2 with Substrates and Products of 2'-O-Methylation of the Cap-1

The structure of Room Temperature Crystal Structure of NSP10/NSP16 From Sars-Cov-2 with Substrates and Products of 2'-O-Methylation of the Cap-1, PDB code: 7jib was solved by M.Wilamowski, G.Minasov, Y.Kim, D.A.Sherrell, L.Shuvalova, A.Lavens, R.Chard, M.Rosas-Lemus, N.Maltseva, R.Jedrzejczak, K.Michalska, K.J.F.Satchell, A.Joachimiak, Center For Structural Genomics Ofinfectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.59 / 2.65
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	170.830, 170.830, 52.738, 90.00, 90.00, 120.00
R / Rfree (%)	15.5 / 18.1

The structure of Room Temperature Crystal Structure of NSP10/NSP16 From Sars-Cov-2 with Substrates and Products of 2'-O-Methylation of the Cap-1 also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Chlorine atom in the Room Temperature Crystal Structure of NSP10/NSP16 From Sars-Cov-2 with Substrates and Products of 2'-O-Methylation of the Cap-1 (pdb code 7jib). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Room Temperature Crystal Structure of NSP10/NSP16 From Sars-Cov-2 with Substrates and Products of 2'-O-Methylation of the Cap-1, PDB code: 7jib:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Room Temperature Crystal Structure of NSP10/NSP16 From Sars-Cov-2 with Substrates and Products of 2'-O-Methylation of the Cap-1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Room Temperature Crystal Structure of NSP10/NSP16 From Sars-Cov-2 with Substrates and Products of 2'-O-Methylation of the Cap-1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl7101 b:0.6 occ:1.00 N A:ALA10 3.2 34.0 1.0 OE1 A:GLN6 3.4 45.9 0.5 O A:HOH7294 3.6 22.6 0.5 CA A:VAL9 3.7 35.0 1.0 C A:VAL9 3.9 34.5 1.0 CB A:ALA10 4.0 34.4 1.0 O A:HOH7293 4.0 60.4 1.0 CA A:ALA10 4.1 33.9 1.0 O A:GLY8 4.2 32.3 1.0 CG1 A:VAL9 4.2 39.9 1.0 O A:ALA10 4.3 38.7 1.0 CD A:GLN6 4.4 47.2 0.5 CB A:VAL9 4.5 37.1 1.0 O A:HOH7203 4.6 46.0 1.0 NE2 A:GLN6 4.7 48.3 0.5 C A:ALA10 4.7 35.6 1.0 N A:VAL9 4.7 34.5 1.0 C A:GLY8 4.9 33.7 1.0

Chlorine binding site 2 out of 2 in the Room Temperature Crystal Structure of NSP10/NSP16 From Sars-Cov-2 with Substrates and Products of 2'-O-Methylation of the Cap-1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Room Temperature Crystal Structure of NSP10/NSP16 From Sars-Cov-2 with Substrates and Products of 2'-O-Methylation of the Cap-1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl7102 b:82.9 occ:1.00 N A:ASN43 3.2 37.4 1.0 O A:HOH7297 3.2 49.0 1.0 NZ A:LYS76 3.5 80.6 1.0 CG A:ASN43 3.5 39.8 1.0 CB A:ASN43 3.6 38.7 1.0 ND2 A:ASN43 3.7 42.0 1.0 N A:MET42 3.7 37.6 1.0 CB A:MET42 3.9 39.7 1.0 CB A:MET41 3.9 40.1 1.0 OD1 A:ASN43 4.0 41.5 1.0 CA A:ASN43 4.0 37.0 1.0 CA A:MET42 4.1 37.7 1.0 C A:MET42 4.1 37.0 1.0 C A:MET41 4.4 36.9 1.0 CE A:LYS76 4.4 78.3 1.0 CA A:MET41 4.6 38.6 1.0 CG A:MET41 4.7 43.2 1.0 SD A:MET41 4.8 46.0 1.0 CG A:PRO80 4.9 39.0 1.0 CG A:MET42 5.0 41.4 1.0

M.Wilamowski, G.Minasov, Y.Kim, D.A.Sherrell, L.Shuvalova, A.Lavens, R.Chard, M.Rosas-Lemus, N.Maltseva, R.Jedrzejczak, K.Michalska, K.J.F.Satchell, A.Joachimiak, Center For Structural Genomics Of Infectious Diseases(Csgid). Room Temperature Crystal Structure of NSP10/NSP16 From Sars-Cov-2 with Substrates and Products of 2'-O-Methylation of the Cap-1 To Be Published.