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Chlorine in PDB 7kce: Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Compound 2Enzymatic activity of Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Compound 2
All present enzymatic activity of Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Compound 2:
2.5.1.6; Protein crystallography data
The structure of Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Compound 2, PDB code: 7kce
was solved by
A.Padyana,
L.Jin,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Compound 2
(pdb code 7kce). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Compound 2, PDB code: 7kce: Chlorine binding site 1 out of 1 in 7kceGo back to Chlorine Binding Sites List in 7kce
Chlorine binding site 1 out
of 1 in the Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Compound 2
Mono view Stereo pair view
Reference:
Z.Konteatis,
J.Travins,
S.Gross,
K.Marjon,
A.Barnett,
E.Mandley,
B.Nicolay,
R.Nagaraja,
Y.Chen,
Y.Sun,
Z.Liu,
J.Yu,
Z.Ye,
F.Jiang,
W.Wei,
C.Fang,
Y.Gao,
P.Kalev,
M.L.Hyer,
B.Delabarre,
L.Jin,
A.K.Padyana,
L.Dang,
J.Murtie,
S.A.Biller,
Z.Sui,
K.M.Marks.
Discovery of Ag-270, A First-in-Class Oral MAT2A Inhibitor For the Treatment of Tumors with Homozygous Mtap Deletion. J.Med.Chem. 2021.
Page generated: Sat Jul 10 12:49:43 2021
ISSN: ISSN 0022-2623 PubMed: 33829783 DOI: 10.1021/ACS.JMEDCHEM.0C01895 |
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