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Chlorine in PDB 7ksi: Thiophenyl-Pyrazolourea Derivatives As Potent, Brian Penetrant, Orally Bioavailable, and Isoform-Selective JNK3 InhibitorsEnzymatic activity of Thiophenyl-Pyrazolourea Derivatives As Potent, Brian Penetrant, Orally Bioavailable, and Isoform-Selective JNK3 Inhibitors
All present enzymatic activity of Thiophenyl-Pyrazolourea Derivatives As Potent, Brian Penetrant, Orally Bioavailable, and Isoform-Selective JNK3 Inhibitors:
2.7.11.24; Protein crystallography data
The structure of Thiophenyl-Pyrazolourea Derivatives As Potent, Brian Penetrant, Orally Bioavailable, and Isoform-Selective JNK3 Inhibitors, PDB code: 7ksi
was solved by
H.Park,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7ksi:
The structure of Thiophenyl-Pyrazolourea Derivatives As Potent, Brian Penetrant, Orally Bioavailable, and Isoform-Selective JNK3 Inhibitors also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Thiophenyl-Pyrazolourea Derivatives As Potent, Brian Penetrant, Orally Bioavailable, and Isoform-Selective JNK3 Inhibitors
(pdb code 7ksi). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Thiophenyl-Pyrazolourea Derivatives As Potent, Brian Penetrant, Orally Bioavailable, and Isoform-Selective JNK3 Inhibitors, PDB code: 7ksi: Chlorine binding site 1 out of 1 in 7ksiGo back to Chlorine Binding Sites List in 7ksi
Chlorine binding site 1 out
of 1 in the Thiophenyl-Pyrazolourea Derivatives As Potent, Brian Penetrant, Orally Bioavailable, and Isoform-Selective JNK3 Inhibitors
Mono view Stereo pair view
Reference:
Y.Feng,
H.Park,
L.Bauer,
J.C.Ryu,
S.O.Yoon.
Thiophene-Pyrazolourea Derivatives As Potent, Orally Bioavailable, and Isoform-Selective JNK3 Inhibitors. Acs Med.Chem.Lett. V. 12 24 2021.
Page generated: Sat Apr 3 14:40:59 2021
ISSN: ISSN 1948-5875 PubMed: 33488960 DOI: 10.1021/ACSMEDCHEMLETT.0C00533 |
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