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Atomistry » Chlorine » PDB 7kth-7l3e » 7l05 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 7kth-7l3e » 7l05 » |
Chlorine in PDB 7l05: Complex of Novel Maytansinoid M24 Bound to T2R-Ttl (Two Tubulin Alpha/Beta Heterodimers, RB3 Stathmin-Like Domain, and Tubulin Tyrosine Ligase)Protein crystallography data
The structure of Complex of Novel Maytansinoid M24 Bound to T2R-Ttl (Two Tubulin Alpha/Beta Heterodimers, RB3 Stathmin-Like Domain, and Tubulin Tyrosine Ligase), PDB code: 7l05
was solved by
M.C.Franklin,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7l05:
The structure of Complex of Novel Maytansinoid M24 Bound to T2R-Ttl (Two Tubulin Alpha/Beta Heterodimers, RB3 Stathmin-Like Domain, and Tubulin Tyrosine Ligase) also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Complex of Novel Maytansinoid M24 Bound to T2R-Ttl (Two Tubulin Alpha/Beta Heterodimers, RB3 Stathmin-Like Domain, and Tubulin Tyrosine Ligase)
(pdb code 7l05). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Complex of Novel Maytansinoid M24 Bound to T2R-Ttl (Two Tubulin Alpha/Beta Heterodimers, RB3 Stathmin-Like Domain, and Tubulin Tyrosine Ligase), PDB code: 7l05: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 7l05Go back to![]() ![]()
Chlorine binding site 1 out
of 2 in the Complex of Novel Maytansinoid M24 Bound to T2R-Ttl (Two Tubulin Alpha/Beta Heterodimers, RB3 Stathmin-Like Domain, and Tubulin Tyrosine Ligase)
![]() Mono view ![]() Stereo pair view
Chlorine binding site 2 out of 2 in 7l05Go back to![]() ![]()
Chlorine binding site 2 out
of 2 in the Complex of Novel Maytansinoid M24 Bound to T2R-Ttl (Two Tubulin Alpha/Beta Heterodimers, RB3 Stathmin-Like Domain, and Tubulin Tyrosine Ligase)
![]() Mono view ![]() Stereo pair view
Reference:
J.O.Dasilva,
K.Yang,
O.Surriga,
T.Nittoli,
A.Kunz,
M.C.Franklin,
F.J.Delfino,
S.Mao,
F.Zhao,
J.T.Giurleo,
M.P.Kelly,
S.Makonnen,
C.Hickey,
P.Krueger,
R.Foster,
Z.Chen,
M.W.Retter,
R.Slim,
T.M.Young,
W.C.Olson,
G.Thurston,
C.Daly.
A Biparatopic Antibody-Drug Conjugate to Treat Met-Expressing Cancers, Including Those That Are Unresponsive to Met Pathway Blockade. Mol.Cancer Ther. V. 20 1966 2021.
Page generated: Mon Jul 29 23:47:45 2024
ISSN: ESSN 1538-8514 PubMed: 34315762 DOI: 10.1158/1535-7163.MCT-21-0009 |
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