Chlorine in PDB 7ldk: Structure of Human Respiratory Syncytial Virus Nonstructural Protein 2 (NS2)

The structure of Structure of Human Respiratory Syncytial Virus Nonstructural Protein 2 (NS2), PDB code: 7ldk was solved by S.Chatterjee, D.Borek, Z.Otwinowski, G.K.Amarasinghe, D.W.Leung, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.55 / 2.82
Space group	P 62
Cell size a, b, c (Å), α, β, γ (°)	157.646, 157.646, 47.291, 90, 90, 120
R / Rfree (%)	21.2 / 25.6

The binding sites of Chlorine atom in the Structure of Human Respiratory Syncytial Virus Nonstructural Protein 2 (NS2) (pdb code 7ldk). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Structure of Human Respiratory Syncytial Virus Nonstructural Protein 2 (NS2), PDB code: 7ldk:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Structure of Human Respiratory Syncytial Virus Nonstructural Protein 2 (NS2)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Human Respiratory Syncytial Virus Nonstructural Protein 2 (NS2) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl402 b:69.4 occ:1.00 O B:ILE116 3.5 39.9 1.0 O B:HOH511 3.7 17.1 1.0 CG1 B:ILE117 4.2 38.3 1.0 CA B:ILE117 4.4 35.2 1.0 C B:ILE116 4.4 37.4 1.0 CB B:ILE117 4.7 35.8 1.0 N B:ILE117 4.8 34.7 1.0 OD2 B:ASP121 4.8 59.4 1.0 CG2 B:ILE117 5.0 37.5 1.0

Chlorine binding site 2 out of 3 in the Structure of Human Respiratory Syncytial Virus Nonstructural Protein 2 (NS2)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Human Respiratory Syncytial Virus Nonstructural Protein 2 (NS2) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl303 b:83.2 occ:1.00 NE A:ARG50 3.3 36.7 1.0 NH2 A:ARG50 3.7 36.5 1.0 CZ A:ARG50 4.0 35.5 1.0 CB A:ARG50 4.1 36.9 1.0 CG A:ARG50 4.1 37.7 1.0 CD A:ARG50 4.3 36.4 1.0 O A:ARG50 4.6 38.5 1.0 CD2 A:LEU52 4.7 31.6 1.0 CA A:ARG50 5.0 38.0 1.0

Chlorine binding site 3 out of 3 in the Structure of Human Respiratory Syncytial Virus Nonstructural Protein 2 (NS2)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of Human Respiratory Syncytial Virus Nonstructural Protein 2 (NS2) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl304 b:69.5 occ:1.00 NH2 A:ARG38 3.6 44.1 1.0 NH1 A:ARG38 4.0 45.5 1.0 CZ A:ARG38 4.3 43.7 1.0 O A:ASP33 4.7 45.6 1.0 O A:HOH405 5.0 35.3 1.0 O A:HOH414 5.0 46.7 1.0

J.Pei, N.D.Wagner, A.J.Zou, S.Chatterjee, D.Borek, A.R.Cole, P.J.Kim, C.F.Basler, Z.Otwinowski, M.L.Gross, G.K.Amarasinghe, D.W.Leung. Structural Basis For Ifn Antagonism By Human Respiratory Syncytial Virus Nonstructural Protein 2. Proc.Natl.Acad.Sci.Usa V. 118 2021.
ISSN: ESSN 1091-6490
PubMed: 33649232
DOI: 10.1073/PNAS.2020587118