Chlorine in PDB 7ljc: Allosteric Modulator LY3154207 Binding to Skf-81297-Bound Dopamine Receptor 1 in Complex with Minigs Protein

The binding sites of Chlorine atom in the Allosteric Modulator LY3154207 Binding to Skf-81297-Bound Dopamine Receptor 1 in Complex with Minigs Protein (pdb code 7ljc). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Allosteric Modulator LY3154207 Binding to Skf-81297-Bound Dopamine Receptor 1 in Complex with Minigs Protein, PDB code: 7ljc:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Allosteric Modulator LY3154207 Binding to Skf-81297-Bound Dopamine Receptor 1 in Complex with Minigs Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Allosteric Modulator LY3154207 Binding to Skf-81297-Bound Dopamine Receptor 1 in Complex with Minigs Protein within 5.0Å range: probe atom residue distance (Å) B Occ R:Cl501 b:87.6 occ:1.00 CL01 R:SK0501 0.0 87.6 1.0 C04 R:SK0501 1.7 51.8 1.0 C06 R:SK0501 2.7 41.5 1.0 C02 R:SK0501 2.7 37.0 1.0 C09 R:SK0501 2.9 38.2 1.0 O02 R:SK0501 2.9 60.5 1.0 OG R:SER202 3.3 77.0 1.0 CZ R:PHE289 3.5 31.1 1.0 OG1 R:THR108 3.6 51.2 1.0 C05 R:SK0501 4.0 43.6 1.0 C10 R:SK0501 4.0 41.7 1.0 CE1 R:PHE289 4.0 32.1 1.0 C01 R:SK0501 4.0 34.4 1.0 CB R:SER202 4.2 59.7 1.0 CB R:SER107 4.2 56.8 1.0 O R:ILE104 4.3 59.4 1.0 N R:THR108 4.4 27.6 1.0 C03 R:SK0501 4.5 42.9 1.0 CE2 R:PHE289 4.6 31.8 1.0 CE2 R:PHE288 4.6 51.4 1.0 OG R:SER198 4.7 84.4 1.0 CA R:ILE104 4.7 27.7 1.0 CB R:THR108 4.8 38.7 1.0 CA R:THR108 4.8 25.7 1.0 C R:SER107 4.8 40.5 1.0 O R:ASP103 4.9 58.5 1.0 C R:ILE104 5.0 31.0 1.0 CG2 R:ILE104 5.0 39.6 1.0

Chlorine binding site 2 out of 3 in the Allosteric Modulator LY3154207 Binding to Skf-81297-Bound Dopamine Receptor 1 in Complex with Minigs Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Allosteric Modulator LY3154207 Binding to Skf-81297-Bound Dopamine Receptor 1 in Complex with Minigs Protein within 5.0Å range: probe atom residue distance (Å) B Occ R:Cl502 b:59.6 occ:1.00 CL9 R:G4C502 0.0 59.6 1.0 C08 R:G4C502 1.8 59.6 1.0 C10 R:G4C502 2.7 59.6 1.0 C07 R:G4C502 2.7 59.6 1.0 C06 R:G4C502 3.0 59.6 1.0 NH2 R:ARG130 3.6 90.2 1.0 CZ R:ARG130 3.7 78.3 1.0 O15 R:G4C502 3.7 59.6 1.0 C05 R:G4C502 3.8 59.6 1.0 NH1 R:ARG130 3.8 85.1 1.0 NE1 R:TRP123 3.9 29.7 1.0 C11 R:G4C502 4.0 59.6 1.0 C13 R:G4C502 4.0 59.6 1.0 CE2 R:TRP123 4.2 20.8 1.0 CZ2 R:TRP123 4.2 30.4 1.0 NE R:ARG130 4.2 52.3 1.0 C12 R:G4C502 4.5 59.6 1.0 CD1 R:TRP123 4.7 23.8 1.0

Chlorine binding site 3 out of 3 in the Allosteric Modulator LY3154207 Binding to Skf-81297-Bound Dopamine Receptor 1 in Complex with Minigs Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Allosteric Modulator LY3154207 Binding to Skf-81297-Bound Dopamine Receptor 1 in Complex with Minigs Protein within 5.0Å range: probe atom residue distance (Å) B Occ R:Cl502 b:59.6 occ:1.00 CL4 R:G4C502 0.0 59.6 1.0 C13 R:G4C502 1.8 59.6 1.0 C12 R:G4C502 2.7 59.6 1.0 C07 R:G4C502 2.7 59.6 1.0 C06 R:G4C502 3.1 59.6 1.0 C05 R:G4C502 3.5 59.6 1.0 C17 R:G4C502 3.6 59.6 1.0 CG R:TRP123 3.8 30.6 1.0 CD2 R:TRP123 3.8 22.0 1.0 CB R:TRP123 3.8 43.0 1.0 CE3 R:TRP123 3.9 31.6 1.0 O R:ARG130 3.9 59.2 1.0 CA R:TYR131 3.9 32.2 1.0 N04 R:G4C502 4.0 59.6 1.0 O15 R:G4C502 4.0 59.6 1.0 C11 R:G4C502 4.0 59.6 1.0 C08 R:G4C502 4.0 59.6 1.0 C16 R:G4C502 4.2 59.6 1.0 CD1 R:TYR131 4.3 33.7 1.0 C R:ARG130 4.3 36.3 1.0 N R:TYR131 4.3 37.6 1.0 CB R:LYS134 4.3 47.2 1.0 CB R:MET135 4.5 55.0 1.0 N R:MET135 4.5 37.3 1.0 C10 R:G4C502 4.5 59.6 1.0 CB R:TYR131 4.6 37.8 1.0 CD1 R:TRP123 4.6 23.8 1.0 CG R:ARG130 4.6 52.1 1.0 CE2 R:TRP123 4.6 20.8 1.0 CZ3 R:TRP123 4.7 38.5 1.0 CE R:MET135 4.8 80.7 1.0 O R:TYR131 4.9 70.2 1.0 C R:TYR131 4.9 40.7 1.0 CA R:TRP123 4.9 32.4 1.0 CG R:TYR131 4.9 37.5 1.0 CA R:MET135 4.9 45.6 1.0

Y.Zhuang, B.Krumm, H.Zhang, X.E.Zhou, Y.Wang, J.Guo, X.-P.Huang, Y.Liu, L.Wang, X.Cheng, Y.Jiang, H.Jiang, K.Melcher, C.Zhang, W.Yi, B.L.Roth, Y.Zhang, H.E.Xu. Mechanism of Dopamine Binding and Allosteric Modulation of the Human D1 Dopamine Receptor Biorxiv 2021.
DOI: 10.1101/2021.02.07.430101