Chlorine in PDB 7m17: Sn-407-LRRC8A in MSP1E3D1 Lipid Nanodiscs (Pose-1)

The binding sites of Chlorine atom in the Sn-407-LRRC8A in MSP1E3D1 Lipid Nanodiscs (Pose-1) (pdb code 7m17). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Sn-407-LRRC8A in MSP1E3D1 Lipid Nanodiscs (Pose-1), PDB code: 7m17:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Sn-407-LRRC8A in MSP1E3D1 Lipid Nanodiscs (Pose-1)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Sn-407-LRRC8A in MSP1E3D1 Lipid Nanodiscs (Pose-1) within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl902 b:85.8 occ:1.00 CL15 C:YNJ902 0.0 85.8 1.0 C11 C:YNJ902 1.8 85.8 1.0 C10 C:YNJ902 2.8 85.8 1.0 C12 C:YNJ902 2.8 85.8 1.0 O14 C:YNJ902 3.1 85.8 1.0 CL16 C:YNJ902 3.2 85.8 1.0 C13 C:YNJ902 3.4 85.8 1.0 C09 C:YNJ902 4.1 85.8 1.0 C07 C:YNJ902 4.1 85.8 1.0 C08 C:YNJ902 4.6 85.8 1.0 CB D:ARG103 4.7 70.1 1.0 C05 C:YNJ902 4.8 85.8 1.0 N D:ARG103 5.0 70.1 1.0

Chlorine binding site 2 out of 2 in the Sn-407-LRRC8A in MSP1E3D1 Lipid Nanodiscs (Pose-1)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Sn-407-LRRC8A in MSP1E3D1 Lipid Nanodiscs (Pose-1) within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl902 b:85.8 occ:1.00 CL16 C:YNJ902 0.0 85.8 1.0 C10 C:YNJ902 1.8 85.8 1.0 C11 C:YNJ902 2.8 85.8 1.0 C09 C:YNJ902 2.8 85.8 1.0 O17 C:YNJ902 3.0 85.8 1.0 CL15 C:YNJ902 3.2 85.8 1.0 C20 C:YNJ902 3.8 85.8 1.0 CD E:ARG103 4.0 68.0 1.0 C19 C:YNJ902 4.0 85.8 1.0 NH1 E:ARG103 4.0 68.0 1.0 C12 C:YNJ902 4.1 85.8 1.0 C08 C:YNJ902 4.1 85.8 1.0 NH1 D:ARG103 4.1 70.1 1.0 C18 C:YNJ902 4.1 85.8 1.0 CD D:ARG103 4.3 70.1 1.0 C22 C:YNJ902 4.3 85.8 1.0 C21 C:YNJ902 4.6 85.8 1.0 C07 C:YNJ902 4.6 85.8 1.0 NE E:ARG103 4.8 68.0 1.0 CZ E:ARG103 4.8 68.0 1.0 CB E:ARG103 4.8 68.0 1.0 CG E:ARG103 4.9 68.0 1.0

S.K.Gunasekar, L.Xie, P.R.Chheda, C.Kang, D.M.Kern, C.My-Ta, A.Kumar, J.Maurer, E.E.Gerber, W.J.Grzesik, M.Elliot-Hudson, Y.Zhang, C.A.Kulkarni, I.Samuel, J.K.Smith, P.Nau, Y.Imai, R.D.Sheldon, E.B.Taylor, D.J.Lerner, A.W.Norris, S.G.Brohawn, R.Kerns, R.Sah. Small Molecule SWELL1-LRRC8 Complex Induction Improves Glycemic Control and Nonalcoholic Fatty Liver Disease in Murine Type 2 Diabetes Biorxiv 2021.
DOI: 10.1101/2021.02.28.432901