Chlorine in PDB 7mgw: 5-Ht Bound Serotonin Transporter Reconstituted in Lipid Nanodisc in Nacl in Occluded Conformation

The binding sites of Chlorine atom in the 5-Ht Bound Serotonin Transporter Reconstituted in Lipid Nanodisc in Nacl in Occluded Conformation (pdb code 7mgw). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the 5-Ht Bound Serotonin Transporter Reconstituted in Lipid Nanodisc in Nacl in Occluded Conformation, PDB code: 7mgw:

Chlorine binding site 1 out of 1 in the 5-Ht Bound Serotonin Transporter Reconstituted in Lipid Nanodisc in Nacl in Occluded Conformation


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of 5-Ht Bound Serotonin Transporter Reconstituted in Lipid Nanodisc in Nacl in Occluded Conformation within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl701 b:186.8 occ:1.00 OG A:SER372 2.7 170.3 1.0 OH A:TYR121 2.8 188.7 1.0 OE1 A:GLN332 3.1 188.7 1.0 CD1 A:PHE105 3.4 183.1 1.0 CD1 A:ILE333 3.5 180.6 1.0 CB A:SER372 3.5 170.3 1.0 OD1 A:ASN101 3.5 178.3 1.0 CZ A:TYR121 3.6 188.7 1.0 CE1 A:TYR121 3.7 188.7 1.0 CE1 A:PHE105 3.9 183.1 1.0 CD A:GLN332 4.2 188.7 1.0 CG A:PHE105 4.2 183.1 1.0 CB A:PHE105 4.5 183.1 1.0 CG A:ASN101 4.6 178.3 1.0 OG A:SER336 4.6 166.8 1.0 CG1 A:ILE333 4.7 180.6 1.0 NE2 A:GLN332 4.7 188.7 1.0 CB A:SER336 4.7 166.8 1.0 CA A:ILE333 4.7 180.6 1.0 CE2 A:TYR121 4.7 188.7 1.0 CB A:ILE333 4.8 180.6 1.0 ND2 A:ASN101 4.9 178.3 1.0 CA A:SER372 4.9 170.3 1.0 CD1 A:TYR121 5.0 188.7 1.0 CZ A:PHE105 5.0 183.1 1.0

D.Yang, E.Gouaux. Illumination of Serotonin Transporter Mechanism and Role of the Allosteric Site. Sci Adv V. 7 L3857 2021.
ISSN: ESSN 2375-2548
PubMed: 34851672
DOI: 10.1126/SCIADV.ABL3857