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Chlorine in PDB 7nwc: Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 2Enzymatic activity of Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 2
All present enzymatic activity of Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 2:
2.6.1.42; Protein crystallography data
The structure of Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 2, PDB code: 7nwc
was solved by
R.C.Hillig,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7nwc:
The structure of Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 2 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 2
(pdb code 7nwc). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 2, PDB code: 7nwc: Jump to Chlorine binding site number: 1; 2; 3; 4; Chlorine binding site 1 out of 4 in 7nwcGo back to Chlorine Binding Sites List in 7nwc
Chlorine binding site 1 out
of 4 in the Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 2
Mono view Stereo pair view
Chlorine binding site 2 out of 4 in 7nwcGo back to Chlorine Binding Sites List in 7nwc
Chlorine binding site 2 out
of 4 in the Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 2
Mono view Stereo pair view
Chlorine binding site 3 out of 4 in 7nwcGo back to Chlorine Binding Sites List in 7nwc
Chlorine binding site 3 out
of 4 in the Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 2
Mono view Stereo pair view
Chlorine binding site 4 out of 4 in 7nwcGo back to Chlorine Binding Sites List in 7nwc
Chlorine binding site 4 out
of 4 in the Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 2
Mono view Stereo pair view
Reference:
J.Gunther,
R.C.Hillig,
K.Zimmermann,
S.Kaulfuss,
C.Lemos,
D.Nguyen,
H.Rehwinkel,
M.Habgood,
C.Lechner,
R.Neuhaus,
U.Ganzer,
M.Drewes,
J.Chai,
L.Bouche.
Bay-069, A Novel (Trifluoromethyl)Pyrimidinedione-Based BCAT1/2 Inhibitor and Chemical Probe. J.Med.Chem. V. 65 14366 2022.
Page generated: Tue Apr 4 20:57:30 2023
ISSN: ISSN 0022-2623 PubMed: 36261130 DOI: 10.1021/ACS.JMEDCHEM.2C00441 |
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