Chlorine in PDB 7o6m: 14-3-3 Sigma with Rela/P65 Binding Site PS45 and Covalently Bound TCF521-097

Protein crystallography data

The structure of 14-3-3 Sigma with Rela/P65 Binding Site PS45 and Covalently Bound TCF521-097, PDB code: 7o6m was solved by M.Wolter, C.Ottmann, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 34.13 / 1.40
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 82.328, 112.518, 62.677, 90, 90, 90
R / Rfree (%) 17.6 / 20.1

Other elements in 7o6m:

The structure of 14-3-3 Sigma with Rela/P65 Binding Site PS45 and Covalently Bound TCF521-097 also contains other interesting chemical elements:

Calcium (Ca) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the 14-3-3 Sigma with Rela/P65 Binding Site PS45 and Covalently Bound TCF521-097 (pdb code 7o6m). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the 14-3-3 Sigma with Rela/P65 Binding Site PS45 and Covalently Bound TCF521-097, PDB code: 7o6m:

Chlorine binding site 1 out of 1 in 7o6m

Go back to Chlorine Binding Sites List in 7o6m
Chlorine binding site 1 out of 1 in the 14-3-3 Sigma with Rela/P65 Binding Site PS45 and Covalently Bound TCF521-097


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of 14-3-3 Sigma with Rela/P65 Binding Site PS45 and Covalently Bound TCF521-097 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl303

b:17.3
occ:1.00
O A:HOH523 2.2 27.2 1.0
O A:GLU110 2.3 17.7 1.0
O A:HOH584 2.4 22.9 1.0
OE2 A:GLU35 2.4 19.9 1.0
OE1 A:GLU35 2.8 24.7 1.0
CD A:GLU35 2.9 24.3 1.0
C A:GLU110 3.5 17.7 1.0
N A:GLY112 4.0 17.2 1.0
O A:HOH592 4.1 32.4 1.0
CA A:GLU110 4.4 14.8 1.0
CG A:GLU35 4.4 16.3 1.0
N A:ALA111 4.5 14.4 1.0
CB A:GLU110 4.5 16.6 1.0
O A:HOH462 4.5 27.0 1.0
CA A:ALA111 4.5 13.9 1.0
OE1 A:GLU110 4.6 24.7 1.0
C A:ALA111 4.7 15.5 1.0
O A:HOH456 4.7 32.6 1.0
CA A:GLY112 4.8 16.8 1.0
O A:HOH539 5.0 24.9 1.0

Reference:

M.Wolter, D.Valenti, P.J.Cossar, S.Hristeva, L.M.Levy, T.Genski, T.Hoffmann, L.Brunsveld, D.Tzalis, C.Ottmann. An Exploration of Chemical Properties Required For Cooperative Stabilization of the 14-3-3 Interaction with Nf-Kappa B-Utilizing A Reversible Covalent Tethering Approach. J.Med.Chem. 2021.
ISSN: ISSN 0022-2623
PubMed: 34076416
DOI: 10.1021/ACS.JMEDCHEM.1C00401
Page generated: Sat Jul 10 13:08:52 2021

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy