Chlorine in PDB 7ocf: Active State GLUA1/A2 Ampa Receptor in Complex with Tarp Gamma 8 and CNIH2 (Lbd-Tmd)

The binding sites of Chlorine atom in the Active State GLUA1/A2 Ampa Receptor in Complex with Tarp Gamma 8 and CNIH2 (Lbd-Tmd) (pdb code 7ocf). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Active State GLUA1/A2 Ampa Receptor in Complex with Tarp Gamma 8 and CNIH2 (Lbd-Tmd), PDB code: 7ocf:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Active State GLUA1/A2 Ampa Receptor in Complex with Tarp Gamma 8 and CNIH2 (Lbd-Tmd)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Active State GLUA1/A2 Ampa Receptor in Complex with Tarp Gamma 8 and CNIH2 (Lbd-Tmd) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1401 b:42.7 occ:1.00 CL A:CYZ1401 0.0 42.7 1.0 C13 A:CYZ1401 1.7 42.7 1.0 N3 A:CYZ1401 2.6 42.7 1.0 C14 A:CYZ1401 2.7 42.7 1.0 C12 A:CYZ1401 2.7 42.7 1.0 S2 A:CYZ1401 3.2 42.7 1.0 CD2 A:LEU755 3.3 42.2 1.0 O4 A:CYZ1401 3.9 42.7 1.0 C11 A:CYZ1401 4.0 42.7 1.0 C10 A:CYZ1401 4.0 42.7 1.0 CA A:ASP756 4.0 41.5 1.0 N A:ASP756 4.1 41.5 1.0 CB A:ASP756 4.3 41.5 1.0 C A:LEU755 4.4 42.2 1.0 C9 A:CYZ1401 4.5 42.7 1.0 O3 A:CYZ1401 4.5 42.7 1.0 CG A:LEU755 4.6 42.2 1.0 O A:LEU755 4.6 42.2 1.0 CB A:LEU755 4.7 42.2 1.0

Chlorine binding site 2 out of 4 in the Active State GLUA1/A2 Ampa Receptor in Complex with Tarp Gamma 8 and CNIH2 (Lbd-Tmd)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Active State GLUA1/A2 Ampa Receptor in Complex with Tarp Gamma 8 and CNIH2 (Lbd-Tmd) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1401 b:62.7 occ:1.00 CL B:CYZ1401 0.0 62.7 1.0 C13 B:CYZ1401 1.7 62.7 1.0 N3 B:CYZ1401 2.6 62.7 1.0 C14 B:CYZ1401 2.7 62.7 1.0 C12 B:CYZ1401 2.7 62.7 1.0 S2 B:CYZ1401 3.2 62.7 1.0 N B:ASP760 3.6 71.2 1.0 CB B:LEU759 3.6 61.0 1.0 C B:LEU759 3.7 61.0 1.0 CA B:ASP760 3.8 71.2 1.0 O B:LEU759 3.9 61.0 1.0 O3 B:CYZ1401 4.0 62.7 1.0 C11 B:CYZ1401 4.0 62.7 1.0 C10 B:CYZ1401 4.0 62.7 1.0 CA B:LEU759 4.3 61.0 1.0 CB B:ASP760 4.3 71.2 1.0 O4 B:CYZ1401 4.4 62.7 1.0 C9 B:CYZ1401 4.5 62.7 1.0 CG B:LEU759 4.6 61.0 1.0 OD1 B:ASP760 4.7 71.2 1.0 O B:PHE495 4.8 41.6 1.0 CB A:SER725 4.8 65.5 1.0 CB B:LYS763 4.8 65.3 1.0

Chlorine binding site 3 out of 4 in the Active State GLUA1/A2 Ampa Receptor in Complex with Tarp Gamma 8 and CNIH2 (Lbd-Tmd)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Active State GLUA1/A2 Ampa Receptor in Complex with Tarp Gamma 8 and CNIH2 (Lbd-Tmd) within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1401 b:40.1 occ:1.00 CL C:CYZ1401 0.0 40.1 1.0 C13 C:CYZ1401 1.7 40.1 1.0 N3 C:CYZ1401 2.6 40.1 1.0 C14 C:CYZ1401 2.7 40.1 1.0 C12 C:CYZ1401 2.7 40.1 1.0 S2 C:CYZ1401 3.2 40.1 1.0 CD2 C:LEU755 3.3 41.6 1.0 O4 C:CYZ1401 3.9 40.1 1.0 C11 C:CYZ1401 4.0 40.1 1.0 C10 C:CYZ1401 4.0 40.1 1.0 CA C:ASP756 4.0 41.8 1.0 N C:ASP756 4.1 41.8 1.0 CB C:ASP756 4.3 41.8 1.0 C C:LEU755 4.4 41.6 1.0 C9 C:CYZ1401 4.5 40.1 1.0 O3 C:CYZ1401 4.5 40.1 1.0 CG C:LEU755 4.5 41.6 1.0 O C:LEU755 4.6 41.6 1.0 CB C:LEU755 4.7 41.6 1.0

Chlorine binding site 4 out of 4 in the Active State GLUA1/A2 Ampa Receptor in Complex with Tarp Gamma 8 and CNIH2 (Lbd-Tmd)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Active State GLUA1/A2 Ampa Receptor in Complex with Tarp Gamma 8 and CNIH2 (Lbd-Tmd) within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl1401 b:62.7 occ:1.00 CL D:CYZ1401 0.0 62.7 1.0 C13 D:CYZ1401 1.7 62.7 1.0 N3 D:CYZ1401 2.6 62.7 1.0 C14 D:CYZ1401 2.7 62.7 1.0 C12 D:CYZ1401 2.7 62.7 1.0 S2 D:CYZ1401 3.2 62.7 1.0 N D:ASP760 3.6 71.2 1.0 CB D:LEU759 3.6 61.0 1.0 C D:LEU759 3.7 61.0 1.0 CA D:ASP760 3.8 71.2 1.0 O D:LEU759 3.9 61.0 1.0 O3 D:CYZ1401 4.0 62.7 1.0 C11 D:CYZ1401 4.0 62.7 1.0 C10 D:CYZ1401 4.0 62.7 1.0 CA D:LEU759 4.3 61.0 1.0 CB D:ASP760 4.3 71.2 1.0 O4 D:CYZ1401 4.4 62.7 1.0 C9 D:CYZ1401 4.5 62.7 1.0 CG D:LEU759 4.6 61.0 1.0 OD1 D:ASP760 4.7 71.2 1.0 O D:PHE495 4.8 41.6 1.0 CB C:SER725 4.8 64.6 1.0 CB D:LYS763 4.8 65.3 1.0

D.Zhang, J.F.Watson, P.M.Matthews, O.Cais, I.H.Greger. Gating and Modulation of A Hetero-Octameric Ampa Glutamate Receptor Nature 2021.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-021-03613-0