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Chlorine in PDB 7onr: PARP1 Catalytic Domain in Complex with 8-Chloroquinazolinone-Based Inhibitor (Compound 9)Enzymatic activity of PARP1 Catalytic Domain in Complex with 8-Chloroquinazolinone-Based Inhibitor (Compound 9)
All present enzymatic activity of PARP1 Catalytic Domain in Complex with 8-Chloroquinazolinone-Based Inhibitor (Compound 9):
2.4.2.30; Protein crystallography data
The structure of PARP1 Catalytic Domain in Complex with 8-Chloroquinazolinone-Based Inhibitor (Compound 9), PDB code: 7onr
was solved by
M.Schimpl,
A.Balazs,
D.Barratt,
M.Bista,
M.Chuba,
S.L.Degorce,
P.Difruscia,
K.Embrey,
A.Ghosh,
S.Gill,
A.Gunnarsson,
S.Hande,
P.Hemsley,
G.Illuzzi,
J.Lane,
C.Larner,
E.Leo,
A.Madin,
S.Martin,
L.Mcwilliams,
J.Orme,
F.Pachl,
M.Packer,
A.Pike,
A.D.Staniszewska,
V.Talbot,
E.Underwood,
G.J.Varnes,
A.Zhang,
X.Zheng,
J.W.Johannes,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the PARP1 Catalytic Domain in Complex with 8-Chloroquinazolinone-Based Inhibitor (Compound 9)
(pdb code 7onr). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the PARP1 Catalytic Domain in Complex with 8-Chloroquinazolinone-Based Inhibitor (Compound 9), PDB code: 7onr: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 7onrGo back to Chlorine Binding Sites List in 7onr
Chlorine binding site 1 out
of 2 in the PARP1 Catalytic Domain in Complex with 8-Chloroquinazolinone-Based Inhibitor (Compound 9)
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 7onrGo back to Chlorine Binding Sites List in 7onr
Chlorine binding site 2 out
of 2 in the PARP1 Catalytic Domain in Complex with 8-Chloroquinazolinone-Based Inhibitor (Compound 9)
Mono view Stereo pair view
Reference:
J.W.Johannes,
M.Schimpl,
A.Balazs,
D.Barratt,
M.Bista,
M.Chuba,
S.L.Degorce,
P.Difruscia,
K.Embrey,
A.Ghosh,
S.Gill,
A.Gunnarsson,
S.Hande,
P.Hemsley,
G.Illuzzi,
J.Lane,
C.Larner,
E.Leo,
A.Madin,
S.Martin,
L.Mcwilliams,
J.Orme,
F.Pachl,
M.Packer,
A.Pike,
A.D.Staniszewska,
V.Talbot,
E.Underwood,
G.J.Varnes,
A.Zhang,
X.Zheng,
J.W.Johannes.
N/A N/A.
Page generated: Fri Sep 24 12:59:26 2021
ISSN: ISSN 0022-2623 |
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