Chlorine in PDB 7owy: Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 3 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site

Enzymatic activity of Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 3 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site

All present enzymatic activity of Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 3 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site:
1.16.3.1;

Protein crystallography data

The structure of Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 3 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site, PDB code: 7owy was solved by C.Pozzi, S.Ciambellotti, G.Tassone, P.Turano, S.Mangani, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 55.57 / 1.55
Space group F 4 3 2
Cell size a, b, c (Å), α, β, γ (°) 184.111, 184.111, 184.111, 90, 90, 90
R / Rfree (%) 15.3 / 17.2

Other elements in 7owy:

The structure of Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 3 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site also contains other interesting chemical elements:

Iron (Fe) 9 atoms
Magnesium (Mg) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 3 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site (pdb code 7owy). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 3 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site, PDB code: 7owy:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in 7owy

Go back to Chlorine Binding Sites List in 7owy
Chlorine binding site 1 out of 4 in the Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 3 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 3 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl213

b:18.0
occ:0.25
 FE A:FE2202 2.5 16.1 0.2
CE1 A:HIS173 3.2 13.9 0.4
NE2 A:HIS173 3.3 13.4 0.6
CE1 A:HIS173 3.3 13.4 0.6
NE2 A:HIS173 3.4 13.5 0.4
CD2 A:LEU169 3.8 12.9 1.0
CD2 A:HIS173 4.4 13.9 0.6
ND1 A:HIS173 4.4 13.4 0.4
ND1 A:HIS173 4.5 13.7 0.6
O A:HOH490 4.6 22.8 0.2
CD2 A:HIS173 4.7 13.6 0.4

Chlorine binding site 2 out of 4 in 7owy

Go back to Chlorine Binding Sites List in 7owy
Chlorine binding site 2 out of 4 in the Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 3 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 3 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl214

b:16.4
occ:0.70
 O A:HOH526 3.2 28.4 1.0
O A:HOH519 3.2 49.3 1.0
N A:PHE12 3.2 10.6 1.0
N A:ASN11 3.4 10.7 1.0
O A:HOH574 3.5 40.5 1.0
O A:PHE12 3.5 11.7 1.0
O A:HOH530 3.6 26.0 1.0
CG A:ARG9 3.6 10.9 1.0
NE A:ARG9 3.6 12.2 1.0
CD A:ARG9 3.6 11.4 1.0
C A:GLN10 3.9 10.4 1.0
O A:HOH486 3.9 24.9 1.0
CA A:GLN10 4.0 10.4 1.0
C A:PHE12 4.0 10.6 1.0
CA A:PHE12 4.0 10.8 1.0
N A:GLN10 4.1 10.5 1.0
CA A:ASN11 4.1 10.5 1.0
C A:ASN11 4.1 9.9 1.0
CB A:PHE12 4.3 10.4 1.0
C A:ARG9 4.4 10.6 1.0
CB A:ARG9 4.6 10.6 1.0
O A:ARG9 4.6 11.9 1.0
O A:GLN10 4.7 10.5 1.0
CZ A:ARG9 4.9 11.9 1.0

Chlorine binding site 3 out of 4 in 7owy

Go back to Chlorine Binding Sites List in 7owy
Chlorine binding site 3 out of 4 in the Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 3 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 3 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl215

b:18.7
occ:0.70
 O A:HOH384 2.9 19.0 1.0
O A:HOH376 3.1 8.6 1.0
NZ A:LYS86 3.2 12.5 0.5
O A:HOH550 3.5 40.6 1.0
O A:HOH537 3.5 35.4 0.5
O A:HOH354 3.9 24.1 1.0
O A:HOH598 3.9 31.0 1.0
CB A:ASP84 4.0 8.8 1.0
CE A:LYS86 4.1 10.9 0.5
OD2 A:ASP84 4.2 10.1 1.0
NZ A:LYS86 4.3 11.0 0.5
CG A:ASP84 4.3 9.4 1.0
N A:ASP84 4.4 8.1 1.0
CE A:LYS86 4.7 11.8 0.5
O A:ASP84 4.7 7.9 1.0
CB A:GLN83 4.7 11.5 1.0
CA A:ASP84 4.8 8.0 1.0
CD A:LYS86 4.8 10.4 0.5
O A:HOH579 4.8 25.6 1.0
O A:HOH639 4.8 46.7 1.0
OE1 A:GLN83 4.9 17.4 1.0

Chlorine binding site 4 out of 4 in 7owy

Go back to Chlorine Binding Sites List in 7owy
Chlorine binding site 4 out of 4 in the Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 3 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Human Mitochondrial Ferritin (Hmtf) Fe(II)-Loaded For 3 Minutes Showing A Peroxide Anion As Bridging Species of Iron Ions in the Ferroxidase Site within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl216

b:14.5
occ:0.70
 O A:HOH391 2.9 25.5 1.0
O A:HOH610 2.9 15.8 1.0
CA A:GLY125 3.6 11.3 1.0
C A:GLY125 3.7 11.7 1.0
CD A:PRO127 3.7 9.7 1.0
N A:PRO127 3.8 9.7 1.0
N A:ASP126 3.9 10.6 1.0
CB A:PRO127 4.0 9.3 1.0
CA A:PRO127 4.1 9.6 1.0
O A:GLY125 4.2 11.4 1.0
C A:ASP126 4.3 10.2 1.0
CG A:PRO127 4.3 9.3 1.0
O A:HOH619 4.4 21.4 0.5
O A:SER122 4.6 12.7 1.0
N A:GLY125 4.6 11.4 1.0
CA A:ASP126 4.7 10.5 1.0
O A:HOH616 4.7 20.9 0.5
O A:ASP126 4.8 10.3 1.0
O A:HOH433 4.9 25.1 1.0
CA A:SER122 5.0 11.9 1.0
O A:ALA121 5.0 11.8 1.0

Reference:

S.Ciambellotti, A.Pratesi, G.Tassone, P.Turano, S.Mangani, C.Pozzi. Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin. Chemistry 2021.
ISSN: ISSN 0947-6539
PubMed: 34343376
DOI: 10.1002/CHEM.202102270
Page generated: Tue Jul 30 02:10:09 2024

Last articles

Zn in 9J0N
Zn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy