Chlorine in PDB 7oxh: Ttslyd with Pseudo-Wild-Type S2 Peptide

All present enzymatic activity of Ttslyd with Pseudo-Wild-Type S2 Peptide:
5.2.1.8;

The structure of Ttslyd with Pseudo-Wild-Type S2 Peptide, PDB code: 7oxh was solved by S.Pazicky, J.Lei, C.Loew, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.63 / 1.70
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	49.225, 49.225, 131.214, 90, 90, 120
R / Rfree (%)	20.3 / 23.8

The structure of Ttslyd with Pseudo-Wild-Type S2 Peptide also contains other interesting chemical elements:

Nickel

(Ni)

2 atoms

The binding sites of Chlorine atom in the Ttslyd with Pseudo-Wild-Type S2 Peptide (pdb code 7oxh). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Ttslyd with Pseudo-Wild-Type S2 Peptide, PDB code: 7oxh:

Chlorine binding site 1 out of 1 in the Ttslyd with Pseudo-Wild-Type S2 Peptide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Ttslyd with Pseudo-Wild-Type S2 Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl207 b:52.6 occ:1.00 OG A:SER151 2.8 98.8 1.0 N A:ALA148 3.2 75.9 1.0 CB A:SER151 3.3 99.0 1.0 N A:LEU30 3.5 44.7 1.0 ND2 A:ASN35 3.6 70.8 1.0 CB A:HIS147 3.6 84.1 1.0 CA A:HIS147 3.7 79.2 1.0 CA A:TYR29 3.7 40.2 1.0 C A:HIS147 3.9 78.1 1.0 CG A:ASN35 4.0 66.1 1.0 C A:TYR29 4.1 42.9 1.0 CB A:ALA148 4.1 74.0 1.0 CB A:ASN35 4.2 51.8 1.0 CA A:ALA148 4.2 76.3 1.0 O A:SER28 4.2 41.1 1.0 CB A:TYR29 4.2 40.5 1.0 ND1 A:HIS147 4.3 96.3 1.0 CG A:HIS147 4.4 95.5 1.0 CB A:LEU30 4.4 44.5 1.0 CA A:SER151 4.5 98.8 1.0 CA A:LEU30 4.6 42.9 1.0 O A:ALA148 4.7 93.9 1.0 N A:TYR29 4.7 39.4 1.0 OD1 A:ASN35 4.8 75.2 1.0 C A:SER28 4.9 47.7 1.0 CD1 B:LEU9 4.9 62.3 1.0 C A:ALA148 5.0 80.5 1.0 O A:GLY146 5.0 78.6 1.0

S.Pazicky, A.A.Werle, J.Lei, C.Low, U.Weininger. Impact of Distant Peptide Substrate Residues on Enzymatic Activity of Slyd. Cell.Mol.Life Sci. V. 79 138 2022.
ISSN: ESSN 1420-9071
PubMed: 35184231
DOI: 10.1007/S00018-022-04179-4