Chlorine in PDB 7p0a: Crystal Structure of the Murine Class I Major Histocompatibility Complex H-2DB in Complex with Lcmv-Derived GP33 Peptide with D- Aminoacid (P3P6F)

The structure of Crystal Structure of the Murine Class I Major Histocompatibility Complex H-2DB in Complex with Lcmv-Derived GP33 Peptide with D- Aminoacid (P3P6F), PDB code: 7p0a was solved by L.Broggini, S.Ricagno, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.41 / 2.43
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	120.649, 125.958, 92.927, 90, 126.63, 90
R / Rfree (%)	21 / 25.6

The binding sites of Chlorine atom in the Crystal Structure of the Murine Class I Major Histocompatibility Complex H-2DB in Complex with Lcmv-Derived GP33 Peptide with D- Aminoacid (P3P6F) (pdb code 7p0a). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of the Murine Class I Major Histocompatibility Complex H-2DB in Complex with Lcmv-Derived GP33 Peptide with D- Aminoacid (P3P6F), PDB code: 7p0a:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of the Murine Class I Major Histocompatibility Complex H-2DB in Complex with Lcmv-Derived GP33 Peptide with D- Aminoacid (P3P6F)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Murine Class I Major Histocompatibility Complex H-2DB in Complex with Lcmv-Derived GP33 Peptide with D- Aminoacid (P3P6F) within 5.0Å range: probe atom residue distance (Å) B Occ E:Cl102 b:76.7 occ:1.00 CG2 E:ILE1 3.7 82.2 1.0 NZ E:LYS3 4.0 77.4 1.0 CD1 E:ILE1 4.4 71.0 1.0 CD D:ARG121 4.6 61.3 1.0 CB E:ILE1 4.8 77.6 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of the Murine Class I Major Histocompatibility Complex H-2DB in Complex with Lcmv-Derived GP33 Peptide with D- Aminoacid (P3P6F)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the Murine Class I Major Histocompatibility Complex H-2DB in Complex with Lcmv-Derived GP33 Peptide with D- Aminoacid (P3P6F) within 5.0Å range: probe atom residue distance (Å) B Occ E:Cl103 b:86.8 occ:1.00 O E:HOH216 2.5 86.0 1.0 N E:THR4 3.6 69.7 1.0 CA E:LYS3 3.7 51.1 1.0 CB E:LYS3 4.0 51.2 1.0 OG1 E:THR4 4.1 92.7 1.0 C E:LYS3 4.2 63.7 1.0 CG2 E:THR4 4.3 82.2 1.0 CB E:THR4 4.6 78.2 1.0 O E:GLN2 4.6 61.4 1.0 CA E:THR4 4.7 64.6 1.0 CG E:LYS3 4.7 46.8 1.0 O E:THR4 4.9 58.6 1.0 N E:LYS3 5.0 46.3 1.0

F.Ballabio, L.Broggini, C.Paissoni, X.Han, K.Peqini, B.M.Sala, R.Sun, T.Sandalova, A.Barbiroli, A.Achour, S.Pellegrino, S.Ricagno, C.Camilloni. L- to D-Amino Acid Substitution in the Immunodominant Lcmv-Derived Epitope GP33 Highlights the Sensitivity of the Tcr Recognition Mechanism For the Mhc/Peptide Structure and Dynamics. Acs Omega V. 7 9622 2022.
ISSN: ESSN 2470-1343
PubMed: 35350306
DOI: 10.1021/ACSOMEGA.1C06964