Chlorine in PDB 7p0t: Crystal Structure of the Murine Class I Major Histocompatibility Complex H-2DB in Complex with Lcmv-Derived GP33 Peptide with D- Aminoacid

The structure of Crystal Structure of the Murine Class I Major Histocompatibility Complex H-2DB in Complex with Lcmv-Derived GP33 Peptide with D- Aminoacid, PDB code: 7p0t was solved by L.Broggini, S.Ricagno, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.20 / 2.61
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	120.512, 124.602, 92.915, 90, 126.87, 90
R / Rfree (%)	19.7 / 24.4

The binding sites of Chlorine atom in the Crystal Structure of the Murine Class I Major Histocompatibility Complex H-2DB in Complex with Lcmv-Derived GP33 Peptide with D- Aminoacid (pdb code 7p0t). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Murine Class I Major Histocompatibility Complex H-2DB in Complex with Lcmv-Derived GP33 Peptide with D- Aminoacid, PDB code: 7p0t:

Chlorine binding site 1 out of 1 in the Crystal Structure of the Murine Class I Major Histocompatibility Complex H-2DB in Complex with Lcmv-Derived GP33 Peptide with D- Aminoacid


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Murine Class I Major Histocompatibility Complex H-2DB in Complex with Lcmv-Derived GP33 Peptide with D- Aminoacid within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl304 b:73.4 occ:1.00 NH2 A:ARG121 3.6 32.3 0.0 CG2 B:ILE1 3.8 61.0 1.0 NE A:ARG121 3.9 27.0 1.0 CD1 B:ILE1 3.9 68.5 1.0 CD A:ARG121 4.0 25.3 0.0 NH1 A:ARG121 4.0 33.5 1.0 NZ B:LYS3 4.1 73.4 1.0 CB B:ILE1 4.1 60.3 1.0 CZ A:ARG121 4.4 32.8 1.0 CG1 B:ILE1 4.6 65.7 1.0 CZ A:ARG121 4.7 29.3 0.0 CG A:ARG121 4.7 22.1 0.0 CG A:ARG121 4.8 22.9 1.0 NE A:ARG121 4.8 27.4 0.0 CD A:ARG121 4.9 16.2 1.0

F.Ballabio, L.Broggini, C.Paissoni, X.Han, K.Peqini, B.M.Sala, R.Sun, T.Sandalova, A.Barbiroli, A.Achour, S.Pellegrino, S.Ricagno, C.Camilloni. L- to D-Amino Acid Substitution in the Immunodominant Lcmv-Derived Epitope GP33 Highlights the Sensitivity of the Tcr Recognition Mechanism For the Mhc/Peptide Structure and Dynamics. Acs Omega V. 7 9622 2022.
ISSN: ESSN 2470-1343
PubMed: 35350306
DOI: 10.1021/ACSOMEGA.1C06964