Chlorine in PDB 7ppr: The Structure of Udp-Glucose Pyrophosphorylase From Aspergillus Fumigatus

All present enzymatic activity of The Structure of Udp-Glucose Pyrophosphorylase From Aspergillus Fumigatus:
2.7.7.9;

The structure of The Structure of Udp-Glucose Pyrophosphorylase From Aspergillus Fumigatus, PDB code: 7ppr was solved by S.Morton, O.G.Raimi, K.Yan, D.M.F.Van Aalten, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	80.00 / 2.57
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	134.16, 152.61, 160.01, 90, 90, 90
R / Rfree (%)	22.7 / 27.7

The binding sites of Chlorine atom in the The Structure of Udp-Glucose Pyrophosphorylase From Aspergillus Fumigatus (pdb code 7ppr). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the The Structure of Udp-Glucose Pyrophosphorylase From Aspergillus Fumigatus, PDB code: 7ppr:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the The Structure of Udp-Glucose Pyrophosphorylase From Aspergillus Fumigatus


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Structure of Udp-Glucose Pyrophosphorylase From Aspergillus Fumigatus within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl607 b:72.7 occ:1.00 N B:ASN194 3.7 76.0 1.0 CB B:ASN194 4.0 76.5 1.0 CA B:PHE193 4.3 57.9 1.0 CA B:ASN194 4.5 71.1 1.0 C B:PHE193 4.6 70.3 1.0 CB B:PHE193 4.6 49.1 1.0 CB B:SER235 4.6 78.7 1.0 O B:ASN194 4.7 68.2 1.0

Chlorine binding site 2 out of 2 in the The Structure of Udp-Glucose Pyrophosphorylase From Aspergillus Fumigatus


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Structure of Udp-Glucose Pyrophosphorylase From Aspergillus Fumigatus within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl608 b:100.1 occ:1.00 OD2 B:ASP189 3.6 58.1 1.0 NH1 B:ARG244 3.6 79.0 1.0 CD B:ARG244 3.7 72.6 1.0 CD1 B:ILE191 3.9 69.3 1.0 CD B:LYS240 4.0 92.3 1.0 OD1 B:ASP189 4.0 49.1 1.0 NE B:ARG244 4.0 82.7 1.0 CZ B:ARG244 4.0 76.8 1.0 CG B:ASP189 4.2 55.8 1.0 CG1 B:ILE191 4.2 65.5 1.0 CG B:LYS240 4.3 85.4 1.0 CG B:ARG244 4.9 74.0 1.0

K.Yan, O.G.Raimi, S.Morton, A.T.Ferenbach, P.Wei, H.Yuan, W.Fang, D.M.F.Van Aalten. Genetic and Structural Validation of Udp-Glucose Pyrophosphorylase As A Novel Antifungal Target Against Aspergillus Fumigatus To Be Published.