Chlorine in PDB 7pw7: Human SMG1-9 Kinase Complex Bound to A SMG1 Inhibitor

All present enzymatic activity of Human SMG1-9 Kinase Complex Bound to A SMG1 Inhibitor:
2.7.11.1;

The structure of Human SMG1-9 Kinase Complex Bound to A SMG1 Inhibitor also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Chlorine atom in the Human SMG1-9 Kinase Complex Bound to A SMG1 Inhibitor (pdb code 7pw7). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human SMG1-9 Kinase Complex Bound to A SMG1 Inhibitor, PDB code: 7pw7:

Chlorine binding site 1 out of 1 in the Human SMG1-9 Kinase Complex Bound to A SMG1 Inhibitor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human SMG1-9 Kinase Complex Bound to A SMG1 Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl3702 b:57.1 occ:1.00 CL39 A:88C3702 0.0 57.1 1.0 C38 A:88C3702 1.8 57.1 1.0 C37 A:88C3702 2.8 57.1 1.0 C09 A:88C3702 2.8 57.1 1.0 O07 A:88C3702 3.0 57.1 1.0 S06 A:88C3702 3.2 57.1 1.0 N03 A:88C3702 3.8 57.1 1.0 C05 A:88C3702 3.9 57.1 1.0 C04 A:88C3702 4.0 57.1 1.0 C36 A:88C3702 4.0 57.1 1.0 C10 A:88C3702 4.1 57.1 1.0 CZ2 A:TRP2207 4.4 58.1 1.0 C11 A:88C3702 4.6 57.1 1.0 O08 A:88C3702 4.6 57.1 1.0 CH2 A:TRP2207 4.7 58.1 1.0 C02 A:88C3702 5.0 57.1 1.0

L.M.Langer, F.Bonneau, Y.Gat, E.Conti. Cryo-Em Reconstructions of Inhibitor-Bound SMG1 Kinase Reveal An Autoinhibitory State Dependent on SMG8. Elife V. 10 2021.
ISSN: ESSN 2050-084X
PubMed: 34698635
DOI: 10.7554/ELIFE.72353