Chlorine in PDB 7q5v: Hif Prolyl Hydroxylase 2 (PHD2/EGLN1) in Complex with N-Oxalylglycine (Nog) and Hif-2 Alpha Codd (523-542)

Enzymatic activity of Hif Prolyl Hydroxylase 2 (PHD2/EGLN1) in Complex with N-Oxalylglycine (Nog) and Hif-2 Alpha Codd (523-542)

All present enzymatic activity of Hif Prolyl Hydroxylase 2 (PHD2/EGLN1) in Complex with N-Oxalylglycine (Nog) and Hif-2 Alpha Codd (523-542):
1.14.11.29;

Protein crystallography data

The structure of Hif Prolyl Hydroxylase 2 (PHD2/EGLN1) in Complex with N-Oxalylglycine (Nog) and Hif-2 Alpha Codd (523-542), PDB code: 7q5v was solved by W.D.Figg Jr, M.A.Mcdonough, R.Chowdhury, Y.Nakashima, C.J.Schofield, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 42.88 / 1.17
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 130.914, 38.322, 42.88, 90, 90, 90
R / Rfree (%) 15.7 / 17.9

Other elements in 7q5v:

The structure of Hif Prolyl Hydroxylase 2 (PHD2/EGLN1) in Complex with N-Oxalylglycine (Nog) and Hif-2 Alpha Codd (523-542) also contains other interesting chemical elements:

Manganese (Mn) 1 atom
Magnesium (Mg) 3 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Hif Prolyl Hydroxylase 2 (PHD2/EGLN1) in Complex with N-Oxalylglycine (Nog) and Hif-2 Alpha Codd (523-542) (pdb code 7q5v). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Hif Prolyl Hydroxylase 2 (PHD2/EGLN1) in Complex with N-Oxalylglycine (Nog) and Hif-2 Alpha Codd (523-542), PDB code: 7q5v:

Chlorine binding site 1 out of 1 in 7q5v

Go back to Chlorine Binding Sites List in 7q5v
Chlorine binding site 1 out of 1 in the Hif Prolyl Hydroxylase 2 (PHD2/EGLN1) in Complex with N-Oxalylglycine (Nog) and Hif-2 Alpha Codd (523-542)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Hif Prolyl Hydroxylase 2 (PHD2/EGLN1) in Complex with N-Oxalylglycine (Nog) and Hif-2 Alpha Codd (523-542) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl509

b:80.8
occ:1.00
 HH22 A:ARG281 1.8 21.1 0.6
HH21 A:ARG281 2.2 21.1 0.6
HH12 A:ARG281 2.2 15.9 0.4
NH2 A:ARG281 2.3 17.6 0.6
HB2 A:SER274 2.6 20.2 0.5
HG A:SER274 2.7 21.8 0.5
OG A:SER274 2.7 18.2 0.5
O A:HOH678 2.8 50.7 1.0
OD1 A:ASP278 2.8 18.1 0.5
O A:HOH635 2.9 14.2 0.5
O A:SER274 2.9 14.2 0.5
O A:SER274 2.9 15.4 0.5
HA A:SER274 3.0 15.9 0.5
NH1 A:ARG281 3.1 13.2 0.4
HA A:SER274 3.1 18.0 0.5
HB2 A:ASP277 3.2 15.7 1.0
CB A:SER274 3.4 16.9 0.5
HH22 A:ARG281 3.4 16.5 0.4
HH11 A:ARG281 3.5 15.9 0.4
CA A:SER274 3.5 15.0 0.5
CG A:ASP278 3.5 15.6 0.5
CA A:SER274 3.6 13.3 0.5
CZ A:ARG281 3.6 16.7 0.6
C A:SER274 3.6 16.5 0.5
C A:SER274 3.6 14.8 0.5
CB A:SER274 3.6 17.6 0.5
HB2 A:ASP278 3.7 23.4 0.5
O A:HOH635 3.7 19.7 0.5
H A:ASP278 3.9 13.5 0.5
H A:ASP278 3.9 18.9 0.5
HB3 A:ASP277 3.9 15.7 1.0
O A:HOH627 3.9 33.6 1.0
OD2 A:ASP278 3.9 19.3 0.5
HH12 A:ARG281 4.0 18.2 0.6
HB3 A:SER274 4.0 20.2 0.5
CZ A:ARG281 4.0 14.1 0.4
HB2 A:SER274 4.0 21.1 0.5
CB A:ASP277 4.0 13.1 1.0
NH2 A:ARG281 4.0 13.8 0.4
N A:ASP278 4.2 11.2 0.5
N A:ASP278 4.2 15.8 0.5
NH1 A:ARG281 4.2 15.1 0.6
OG A:SER274 4.4 23.8 0.5
HB3 A:SER274 4.4 21.1 0.5
HA A:ASP278 4.4 16.3 0.5
HA A:ASP278 4.4 16.5 0.5
HE A:ARG281 4.4 19.0 0.6
NE A:ARG281 4.5 15.8 0.6
CB A:ASP278 4.6 19.5 0.5
CB A:ASP278 4.6 13.9 0.5
CA A:ASP278 4.6 13.7 0.5
CA A:ASP278 4.7 13.6 0.5
O A:HOH623 4.7 22.4 1.0
C A:ASP277 4.7 12.2 1.0
OD2 A:ASP277 4.8 14.2 1.0
N A:SER275 4.9 15.2 1.0
HH21 A:ARG281 4.9 16.5 0.4
HB2 A:ASP278 4.9 16.8 0.5
O A:HOH664 4.9 63.0 1.0
CA A:ASP277 4.9 12.8 1.0
N A:SER274 5.0 13.6 0.5
N A:SER274 5.0 14.7 0.5
CG A:ASP277 5.0 13.1 1.0

Reference:

W.D.Figg Jr, M.A.Mcdonough, R.Chowdhury, Y.Nakashima, C.J.Schofield. Hif Prolyl Hydroxylase 2 (PHD2/EGLN1) in Complex with N-Oxalylglycine (Nog) and Hif-2 Alpha Codd (523-542) To Be Published.
Page generated: Tue Jul 30 03:03:31 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy