Chlorine in PDB 7qg6: Co-Crystal Structure of UPF3A-Rrm-Nops-L with UPF2-MIF4GIII

The structure of Co-Crystal Structure of UPF3A-Rrm-Nops-L with UPF2-MIF4GIII, PDB code: 7qg6 was solved by K.T.Powers, J.C.Bufton, J.A.Szeto, C.Schaffitzel, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	65.25 / 2.95
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	77.677, 108.579, 119.943, 90, 90.1, 90
R / Rfree (%)	20.7 / 26.3

The binding sites of Chlorine atom in the Co-Crystal Structure of UPF3A-Rrm-Nops-L with UPF2-MIF4GIII (pdb code 7qg6). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Co-Crystal Structure of UPF3A-Rrm-Nops-L with UPF2-MIF4GIII, PDB code: 7qg6:

Chlorine binding site 1 out of 1 in the Co-Crystal Structure of UPF3A-Rrm-Nops-L with UPF2-MIF4GIII


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Co-Crystal Structure of UPF3A-Rrm-Nops-L with UPF2-MIF4GIII within 5.0Å range: probe atom residue distance (Å) B Occ F:Cl1102 b:43.0 occ:1.00 N F:LEU916 3.6 53.4 1.0 N F:PHE917 3.6 47.7 1.0 C F:LEU916 4.0 47.2 1.0 CA F:LEU916 4.2 53.6 1.0 CA F:PHE917 4.2 40.7 1.0 O F:GLU914 4.3 66.0 1.0 CB F:LEU916 4.3 36.3 1.0 CB F:PHE917 4.4 44.8 1.0 C F:HIS915 4.6 50.0 1.0 O F:LEU916 4.7 36.4 1.0 CA F:HIS915 4.7 50.8 1.0 CD1 F:PHE917 4.9 37.7 1.0 ND2 F:ASN865 5.0 32.4 1.0

J.C.Bufton, K.T.Powers, J.A.Szeto, C.Toelzer, I.Berger, C.Schaffitzel. Structures of Nonsense-Mediated Mrna Decay Factors UPF3B and UPF3A in Complex with UPF2 Reveal Molecular Basis For Competitive Binding and For Neurodevelopmental Disorder-Causing Mutation. Nucleic Acids Res. V. 50 5934 2022.
ISSN: ESSN 1362-4962
PubMed: 35640974
DOI: 10.1093/NAR/GKAC421