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Chlorine in PDB 7run: Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain Complexed with A Pyrrolo[2,3-D]Pyrimidine Inhibitor.Enzymatic activity of Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain Complexed with A Pyrrolo[2,3-D]Pyrimidine Inhibitor.
All present enzymatic activity of Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain Complexed with A Pyrrolo[2,3-D]Pyrimidine Inhibitor.:
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain Complexed with A Pyrrolo[2,3-D]Pyrimidine Inhibitor., PDB code: 7run
was solved by
C.C.Lee,
G.Spraggon,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain Complexed with A Pyrrolo[2,3-D]Pyrimidine Inhibitor.
(pdb code 7run). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain Complexed with A Pyrrolo[2,3-D]Pyrimidine Inhibitor., PDB code: 7run: Jump to Chlorine binding site number: 1; 2; 3; 4; Chlorine binding site 1 out of 4 in 7runGo back to Chlorine Binding Sites List in 7run
Chlorine binding site 1 out
of 4 in the Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain Complexed with A Pyrrolo[2,3-D]Pyrimidine Inhibitor.
Mono view Stereo pair view
Chlorine binding site 2 out of 4 in 7runGo back to Chlorine Binding Sites List in 7run
Chlorine binding site 2 out
of 4 in the Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain Complexed with A Pyrrolo[2,3-D]Pyrimidine Inhibitor.
Mono view Stereo pair view
Chlorine binding site 3 out of 4 in 7runGo back to Chlorine Binding Sites List in 7run
Chlorine binding site 3 out
of 4 in the Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain Complexed with A Pyrrolo[2,3-D]Pyrimidine Inhibitor.
Mono view Stereo pair view
Chlorine binding site 4 out of 4 in 7runGo back to Chlorine Binding Sites List in 7run
Chlorine binding site 4 out
of 4 in the Crystal Structure of Phosphorylated Ret Tyrosine Kinase Domain Complexed with A Pyrrolo[2,3-D]Pyrimidine Inhibitor.
Mono view Stereo pair view
Reference:
C.J.N.Mathison,
Y.Yang,
J.Nelson,
Z.Huang,
J.Jiang,
D.Chianelli,
P.V.Rucker,
J.Roland,
Y.F.Xie,
R.Epple,
B.Bursulaya,
C.Lee,
M.Y.Gao,
J.Shaffer,
S.Briones,
Y.Sarkisova,
A.Galkin,
L.Li,
N.Li,
C.Li,
S.Hua,
S.Kasibhatla,
J.Kinyamu-Akunda,
R.Kikkawa,
V.Molteni,
J.E.Tellew.
Antitarget Selectivity and Tolerability of Novel Pyrrolo[2,3- D ]Pyrimidine Ret Inhibitors. Acs Med.Chem.Lett. V. 12 1912 2021.
Page generated: Tue Apr 4 21:39:10 2023
ISSN: ISSN 1948-5875 PubMed: 34917254 DOI: 10.1021/ACSMEDCHEMLETT.1C00450 |
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