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Chlorine in PDB 7rwh: Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Agi-41998Enzymatic activity of Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Agi-41998
All present enzymatic activity of Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Agi-41998:
2.5.1.6; Protein crystallography data
The structure of Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Agi-41998, PDB code: 7rwh
was solved by
L.Jin,
A.K.Padyana,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7rwh:
The structure of Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Agi-41998 also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Agi-41998
(pdb code 7rwh). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Agi-41998, PDB code: 7rwh: Chlorine binding site 1 out of 1 in 7rwhGo back to Chlorine Binding Sites List in 7rwh
Chlorine binding site 1 out
of 1 in the Crystal Structure of Human Methionine Adenosyltransferase 2A (MAT2A) in Complex with Sam and Allosteric Inhibitor Agi-41998
Mono view Stereo pair view
Reference:
M.Li,
Z.Konteatis,
N.Nagaraja,
Y.Chen,
S.Zhou,
G.Ma,
S.Gross,
K.Marjon,
M.L.Hyer,
E.Mandley,
M.Lein,
A.K.Padyana,
L.Jin,
S.Tong,
R.Peters,
J.Murtie,
J.Travins,
M.Medeiros,
P.Liu,
V.Frank,
E.T.Judd,
S.A.Biller,
K.M.Marks,
Z.Sui,
S.K.Reznik.
Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads. J.Med.Chem. V. 65 4600 2022.
Page generated: Tue Apr 4 21:39:58 2023
ISSN: ISSN 0022-2623 PubMed: 35293760 DOI: 10.1021/ACS.JMEDCHEM.1C01595 |
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