Chlorine in PDB 7sac: S-(+)-Ketamine Bound GLUN1A-GLUN2B Nmda Receptors at 3.69 Angstrom Resolution

The binding sites of Chlorine atom in the S-(+)-Ketamine Bound GLUN1A-GLUN2B Nmda Receptors at 3.69 Angstrom Resolution (pdb code 7sac). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the S-(+)-Ketamine Bound GLUN1A-GLUN2B Nmda Receptors at 3.69 Angstrom Resolution, PDB code: 7sac:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the S-(+)-Ketamine Bound GLUN1A-GLUN2B Nmda Receptors at 3.69 Angstrom Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of S-(+)-Ketamine Bound GLUN1A-GLUN2B Nmda Receptors at 3.69 Angstrom Resolution within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl903 b:87.0 occ:0.33 CL1 B:JC9903 0.0 87.0 0.3 N1 B:JC9903 1.2 87.0 0.3 C10 B:JC9903 1.6 87.0 0.3 C10 B:JC9903 1.6 87.0 0.3 O1 B:JC9903 1.8 87.0 0.3 C8 B:JC9903 1.8 87.0 0.3 C1 B:JC9903 2.0 87.0 0.3 C7 B:JC9903 2.2 87.0 0.3 N1 B:JC9903 2.2 87.0 0.3 CL1 B:JC9903 2.3 87.0 0.3 C5 B:JC9903 2.4 87.0 0.3 C9 B:JC9903 2.4 87.0 0.3 C11 B:JC9903 2.7 87.0 0.3 C1 B:JC9903 2.8 87.0 0.3 C2 B:JC9903 2.8 87.0 0.3 C7 B:JC9903 2.8 87.0 0.3 C5 B:JC9903 3.1 87.0 0.3 O1 B:JC9903 3.2 87.0 0.3 C8 B:JC9903 3.2 87.0 0.3 C5 B:JC9903 3.3 87.0 0.3 C1 B:JC9903 3.3 87.0 0.3 C4 B:JC9903 3.3 87.0 0.3 C3 B:JC9903 3.4 87.0 0.3 C12 B:JC9903 3.4 87.0 0.3 C8 B:JC9903 3.5 87.0 0.3 O1 B:JC9903 3.6 87.0 0.3 C7 B:JC9903 3.6 87.0 0.3 C6 B:JC9903 3.6 87.0 0.3 C6 B:JC9903 3.7 87.0 0.3 C2 B:JC9903 3.7 87.0 0.3 OG1 D:THR647 3.8 68.8 1.0 C13 B:JC9903 4.0 87.0 0.3 C2 B:JC9903 4.0 87.0 0.3 C3 B:JC9903 4.1 87.0 0.3 C9 B:JC9903 4.1 87.0 0.3 C11 B:JC9903 4.1 87.0 0.3 OG1 A:THR648 4.2 69.0 1.0 C13 B:JC9903 4.2 87.0 0.3 CL1 B:JC9903 4.3 87.0 0.3 CB D:THR647 4.4 68.8 1.0 CG D:LEU643 4.5 69.8 1.0 CA D:ALA644 4.5 68.2 1.0 C12 B:JC9903 4.6 87.0 0.3 O D:LEU643 4.6 69.8 1.0 C6 B:JC9903 4.6 87.0 0.3 N1 B:JC9903 4.7 87.0 0.3 C11 B:JC9903 4.7 87.0 0.3 C3 B:JC9903 4.7 87.0 0.3 CG2 A:THR648 4.8 69.0 1.0 C4 B:JC9903 4.8 87.0 0.3 N D:ALA644 4.8 68.2 1.0 C D:LEU643 4.8 69.8 1.0 C4 B:JC9903 4.9 87.0 0.3 C9 B:JC9903 4.9 87.0 0.3 CG2 D:THR647 5.0 68.8 1.0

Chlorine binding site 2 out of 3 in the S-(+)-Ketamine Bound GLUN1A-GLUN2B Nmda Receptors at 3.69 Angstrom Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of S-(+)-Ketamine Bound GLUN1A-GLUN2B Nmda Receptors at 3.69 Angstrom Resolution within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl903 b:87.0 occ:0.33 CL1 B:JC9903 0.0 87.0 0.3 C2 B:JC9903 0.5 87.0 0.3 C3 B:JC9903 1.0 87.0 0.3 C8 B:JC9903 1.7 87.0 0.3 C1 B:JC9903 1.9 87.0 0.3 C4 B:JC9903 2.2 87.0 0.3 C2 B:JC9903 2.4 87.0 0.3 C11 B:JC9903 2.6 87.0 0.3 C7 B:JC9903 2.7 87.0 0.3 C5 B:JC9903 2.7 87.0 0.3 N1 B:JC9903 2.8 87.0 0.3 C9 B:JC9903 2.8 87.0 0.3 C7 B:JC9903 2.8 87.0 0.3 C7 B:JC9903 2.8 87.0 0.3 C6 B:JC9903 2.8 87.0 0.3 O1 B:JC9903 2.9 87.0 0.3 C5 B:JC9903 2.9 87.0 0.3 C1 B:JC9903 3.1 87.0 0.3 C9 B:JC9903 3.1 87.0 0.3 C3 B:JC9903 3.2 87.0 0.3 C8 B:JC9903 3.3 87.0 0.3 C1 B:JC9903 3.4 87.0 0.3 C12 B:JC9903 3.4 87.0 0.3 C6 B:JC9903 3.4 87.0 0.3 C10 B:JC9903 3.4 87.0 0.3 C10 B:JC9903 3.5 87.0 0.3 N1 B:JC9903 3.7 87.0 0.3 C11 B:JC9903 3.8 87.0 0.3 O1 B:JC9903 3.8 87.0 0.3 C13 B:JC9903 3.9 87.0 0.3 C13 B:JC9903 3.9 87.0 0.3 C9 B:JC9903 4.0 87.0 0.3 CD2 B:LEU643 4.0 82.3 1.0 C8 B:JC9903 4.1 87.0 0.3 N1 B:JC9903 4.1 87.0 0.3 CL1 B:JC9903 4.3 87.0 0.3 C12 B:JC9903 4.4 87.0 0.3 OG1 B:THR647 4.5 83.3 1.0 C10 B:JC9903 4.5 87.0 0.3 C12 B:JC9903 4.5 87.0 0.3 C5 B:JC9903 4.5 87.0 0.3 CG1 A:VAL644 4.5 72.3 1.0 OD1 B:ASN615 4.5 73.0 1.0 C4 B:JC9903 4.5 87.0 0.3 CL1 B:JC9903 4.6 87.0 0.3 C2 B:JC9903 4.7 87.0 0.3 CG B:LEU643 4.7 82.3 1.0 C4 B:JC9903 4.7 87.0 0.3 CD1 B:LEU643 4.9 82.3 1.0

Chlorine binding site 3 out of 3 in the S-(+)-Ketamine Bound GLUN1A-GLUN2B Nmda Receptors at 3.69 Angstrom Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of S-(+)-Ketamine Bound GLUN1A-GLUN2B Nmda Receptors at 3.69 Angstrom Resolution within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl903 b:87.0 occ:0.33 CL1 B:JC9903 0.0 87.0 0.3 C5 B:JC9903 1.3 87.0 0.3 C2 B:JC9903 1.3 87.0 0.3 C1 B:JC9903 1.3 87.0 0.3 C6 B:JC9903 1.4 87.0 0.3 N1 B:JC9903 1.4 87.0 0.3 C8 B:JC9903 1.7 87.0 0.3 C4 B:JC9903 1.7 87.0 0.3 O1 B:JC9903 1.9 87.0 0.3 C3 B:JC9903 2.0 87.0 0.3 C5 B:JC9903 2.1 87.0 0.3 N1 B:JC9903 2.2 87.0 0.3 CL1 B:JC9903 2.3 87.0 0.3 C1 B:JC9903 2.3 87.0 0.3 C3 B:JC9903 2.5 87.0 0.3 C7 B:JC9903 2.5 87.0 0.3 C11 B:JC9903 2.7 87.0 0.3 C7 B:JC9903 2.7 87.0 0.3 O1 B:JC9903 2.7 87.0 0.3 C1 B:JC9903 2.7 87.0 0.3 C2 B:JC9903 2.8 87.0 0.3 C10 B:JC9903 2.8 87.0 0.3 O1 B:JC9903 2.8 87.0 0.3 C10 B:JC9903 2.9 87.0 0.3 C7 B:JC9903 3.0 87.0 0.3 C8 B:JC9903 3.0 87.0 0.3 C4 B:JC9903 3.1 87.0 0.3 C6 B:JC9903 3.1 87.0 0.3 C5 B:JC9903 3.1 87.0 0.3 C9 B:JC9903 3.2 87.0 0.3 N1 B:JC9903 3.5 87.0 0.3 OG1 D:THR647 3.8 68.8 1.0 C9 B:JC9903 3.8 87.0 0.3 C8 B:JC9903 3.9 87.0 0.3 C13 B:JC9903 3.9 87.0 0.3 C10 B:JC9903 4.1 87.0 0.3 C2 B:JC9903 4.1 87.0 0.3 C9 B:JC9903 4.3 87.0 0.3 C11 B:JC9903 4.3 87.0 0.3 C12 B:JC9903 4.3 87.0 0.3 C12 B:JC9903 4.5 87.0 0.3 CL1 B:JC9903 4.6 87.0 0.3 C6 B:JC9903 4.6 87.0 0.3 CB D:THR647 4.7 68.8 1.0 CG2 D:THR647 4.8 68.8 1.0

T.H.Chou, M.Epstein, K.Michalski, E.Fine, P.C.Biggin, H.Furukawa. Structural Insights Into Binding of Therapeutic Channel Blockers in Nmda Receptors. Nat.Struct.Mol.Biol. V. 29 507 2022.
ISSN: ESSN 1545-9985
PubMed: 35637422
DOI: 10.1038/S41594-022-00772-0