Chlorine in PDB 7sb6: Crystal Structure of Ancestral Mammalian Cadherin-23 EC1-2

The structure of Crystal Structure of Ancestral Mammalian Cadherin-23 EC1-2, PDB code: 7sb6 was solved by C.R.Nisler, Y.Narui, M.Sotomayor, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.53 / 2.59
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	118.446, 168.834, 125.276, 90, 90, 90
R / Rfree (%)	20.4 / 24.6

The structure of Crystal Structure of Ancestral Mammalian Cadherin-23 EC1-2 also contains other interesting chemical elements:

Calcium	(Ca)	12 atoms
Potassium	(K)	2 atoms

The binding sites of Chlorine atom in the Crystal Structure of Ancestral Mammalian Cadherin-23 EC1-2 (pdb code 7sb6). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of Ancestral Mammalian Cadherin-23 EC1-2, PDB code: 7sb6:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Crystal Structure of Ancestral Mammalian Cadherin-23 EC1-2


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Ancestral Mammalian Cadherin-23 EC1-2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl305 b:63.9 occ:1.00 NH1 B:ARG91 3.2 66.7 1.0 N B:PHE6 3.3 47.8 1.0 CD B:ARG91 3.6 61.0 1.0 CA B:TYR5 3.9 53.9 1.0 CB B:PHE6 4.0 45.2 1.0 C B:TYR5 4.0 51.8 1.0 CB B:TYR5 4.1 55.5 1.0 CZ B:ARG91 4.1 65.7 1.0 CA B:PHE6 4.1 46.9 1.0 CD2 B:PHE6 4.2 46.2 1.0 O B:PHE6 4.2 47.0 1.0 NE B:ARG91 4.3 63.6 1.0 CG2 B:ILE89 4.4 53.1 1.0 CG B:PHE6 4.5 45.4 1.0 C B:PHE6 4.7 46.9 1.0 CG B:ARG91 4.7 58.6 1.0 CD1 B:ILE89 5.0 62.7 1.0

Chlorine binding site 2 out of 3 in the Crystal Structure of Ancestral Mammalian Cadherin-23 EC1-2


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Ancestral Mammalian Cadherin-23 EC1-2 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl305 b:73.1 occ:1.00 N C:PHE6 3.3 52.7 1.0 NH1 C:ARG91 3.4 73.5 1.0 CD C:ARG91 3.6 67.5 1.0 CA C:TYR5 3.6 56.5 1.0 CB C:TYR5 3.7 59.6 1.0 C C:TYR5 4.0 55.2 1.0 CB C:PHE6 4.1 49.9 1.0 O C:PHE6 4.2 58.2 1.0 CA C:PHE6 4.2 50.8 1.0 CG2 C:ILE89 4.3 60.9 1.0 CZ C:ARG91 4.3 73.4 1.0 CD2 C:PHE6 4.4 49.5 1.0 NE C:ARG91 4.4 71.0 1.0 CD1 C:ILE89 4.4 70.3 1.0 CG C:ARG91 4.7 65.5 1.0 CG C:PHE6 4.7 48.0 1.0 C C:PHE6 4.8 53.5 1.0 O C:PRO4 4.9 55.6 1.0 N C:TYR5 5.0 57.2 1.0

Chlorine binding site 3 out of 3 in the Crystal Structure of Ancestral Mammalian Cadherin-23 EC1-2


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Ancestral Mammalian Cadherin-23 EC1-2 within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl306 b:91.8 occ:1.00 OG1 C:THR13 3.2 60.6 1.0 C B:GLY137 3.4 51.9 1.0 CD2 C:TYR9 3.5 68.7 1.0 CA B:GLY137 3.5 52.6 1.0 N B:ALA138 3.6 51.9 1.0 O B:GLY137 3.7 54.3 1.0 CB C:TYR9 3.8 61.8 1.0 O C:TYR9 4.0 57.3 1.0 CG2 C:THR13 4.1 67.2 1.0 CG C:TYR9 4.1 65.8 1.0 CB C:THR13 4.3 63.3 1.0 CA B:ALA138 4.3 51.0 1.0 C C:TYR9 4.5 55.7 1.0 CE2 C:TYR9 4.5 70.4 1.0 CA C:TYR9 4.6 58.4 1.0 N B:GLY137 4.7 51.8 1.0 CB B:SER141 4.7 49.4 1.0

C.R.Nisler, Y.Narui, M.Sotomayor. Crystal Structure of Ancestral Mammalian Cadherin-23 EC1-2 To Be Published.