Chlorine in PDB 7sci: AM0627 Metallopeptidase From Akkermansia Muciniphila

The structure of AM0627 Metallopeptidase From Akkermansia Muciniphila, PDB code: 7sci was solved by D.Fernandez, C.R.Bertozzi, D.J.Shon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.96 / 1.90
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	101.564, 101.564, 114.626, 90, 90, 120
R / Rfree (%)	17 / 20.2

The structure of AM0627 Metallopeptidase From Akkermansia Muciniphila also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Chlorine atom in the AM0627 Metallopeptidase From Akkermansia Muciniphila (pdb code 7sci). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the AM0627 Metallopeptidase From Akkermansia Muciniphila, PDB code: 7sci:

Chlorine binding site 1 out of 1 in the AM0627 Metallopeptidase From Akkermansia Muciniphila


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of AM0627 Metallopeptidase From Akkermansia Muciniphila within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl611 b:47.2 occ:1.00 NE1 A:TRP321 3.4 23.6 1.0 ND2 A:ASN347 3.4 22.6 1.0 ND1 A:HIS325 3.7 26.1 1.0 CE1 A:HIS325 3.8 27.8 1.0 O A:HOH963 3.8 43.1 1.0 CE2 A:PHE390 4.1 32.6 1.0 CE2 A:TRP321 4.1 23.9 1.0 CZ2 A:TRP321 4.2 23.7 1.0 OD1 A:ASN347 4.2 22.8 1.0 CG A:ASN347 4.3 21.8 1.0 CD1 A:TRP321 4.4 22.6 1.0 CZ A:PHE390 4.6 33.6 1.0 CG A:HIS325 4.6 24.4 1.0 NE2 A:HIS325 4.7 27.2 1.0 O A:HOH1033 4.9 60.8 1.0

D.J.Shon, D.Fernandez, N.M.Riley, M.J.Ferracane, C.R.Bertozzi. Structure-Guided Mutagenesis of A Mucin-Selective Metalloprotease From Akkermansia Muciniphila Alters Substrate Preferences. J.Biol.Chem. V. 298 01917 2022.
ISSN: ESSN 1083-351X
PubMed: 35405095
DOI: 10.1016/J.JBC.2022.101917