Chlorine in PDB 7tcy: The Ubiquitin-Associated Domain of Human Thirty-Eight Negative Kinase I

All present enzymatic activity of The Ubiquitin-Associated Domain of Human Thirty-Eight Negative Kinase I:
2.7.10.2;

The structure of The Ubiquitin-Associated Domain of Human Thirty-Eight Negative Kinase I, PDB code: 7tcy was solved by S.Nawarathnage, R.D.Bunn, C.Stewart, T.Doukov, D.J.Moody, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.03 / 1.54
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	53.734, 88.07, 26.497, 90, 90, 90
R / Rfree (%)	18.9 / 21.4

The structure of The Ubiquitin-Associated Domain of Human Thirty-Eight Negative Kinase I also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Chlorine atom in the The Ubiquitin-Associated Domain of Human Thirty-Eight Negative Kinase I (pdb code 7tcy). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the The Ubiquitin-Associated Domain of Human Thirty-Eight Negative Kinase I, PDB code: 7tcy:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the The Ubiquitin-Associated Domain of Human Thirty-Eight Negative Kinase I


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Ubiquitin-Associated Domain of Human Thirty-Eight Negative Kinase I within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl705 b:26.3 occ:1.00 HE A:ARG626 2.4 24.5 1.0 HZ2 A:LYS629 2.4 30.9 1.0 HD2 A:LYS629 2.9 29.2 1.0 O A:HOH841 3.0 23.0 1.0 HB3 A:TRP653 3.1 22.2 1.0 HA A:ARG626 3.2 20.5 1.0 NE A:ARG626 3.3 20.4 1.0 HH21 A:ARG626 3.3 31.4 1.0 NZ A:LYS629 3.3 25.7 1.0 O B:HOH837 3.3 24.3 1.0 HG22 A:ILE625 3.4 19.2 1.0 HB2 A:ARG626 3.6 20.3 1.0 HZ3 A:LYS629 3.7 30.9 1.0 CD A:LYS629 3.7 24.3 1.0 HZ1 A:LYS629 3.8 30.9 1.0 HD3 A:ARG626 3.9 24.4 1.0 CE A:LYS629 3.9 28.2 1.0 HE3 A:TRP653 3.9 21.2 1.0 HE3 A:LYS629 3.9 33.9 1.0 NH2 A:ARG626 3.9 26.1 1.0 CA A:ARG626 3.9 17.1 1.0 CZ A:ARG626 4.1 19.7 1.0 CB A:TRP653 4.1 18.5 1.0 CD A:ARG626 4.1 20.3 1.0 HD3 A:LYS629 4.1 29.2 1.0 CB A:ARG626 4.2 16.9 1.0 HD21 A:LEU648 4.3 22.9 1.0 N A:ARG626 4.3 13.5 1.0 CG2 A:ILE625 4.3 15.9 1.0 CE3 A:TRP653 4.4 17.6 1.0 HB2 A:TRP653 4.4 22.2 1.0 H A:ARG626 4.5 16.2 1.0 HG21 A:ILE625 4.6 19.2 1.0 CG A:TRP653 4.6 19.9 1.0 O B:HOH843 4.6 31.2 1.0 HB2 A:LYS629 4.7 18.7 1.0 O A:TRP653 4.7 17.8 1.0 HH22 A:ARG626 4.7 31.4 1.0 HG23 A:ILE625 4.7 19.2 1.0 CD2 A:TRP653 4.7 16.8 1.0 HG3 A:LYS629 4.8 19.9 1.0 C A:ILE625 4.8 15.3 1.0 CG A:ARG626 4.8 23.4 1.0 HE2 A:LYS629 4.8 33.9 1.0 CG A:LYS629 4.8 16.5 1.0 HB B:VAL621 4.9 21.5 1.0 HG23 B:VAL622 4.9 24.3 1.0 HD2 A:ARG626 4.9 24.4 1.0 HA A:TRP653 4.9 18.3 1.0 HB A:ILE625 5.0 18.8 1.0

Chlorine binding site 2 out of 2 in the The Ubiquitin-Associated Domain of Human Thirty-Eight Negative Kinase I


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Ubiquitin-Associated Domain of Human Thirty-Eight Negative Kinase I within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl706 b:74.6 occ:1.00 HH21 A:ARG660 3.2 48.6 1.0 NH2 A:ARG660 3.8 40.5 1.0 HH22 A:ARG660 3.9 48.6 1.0 O A:HOH824 4.4 25.2 1.0 HE A:ARG660 4.7 34.8 1.0 CZ A:ARG660 4.8 25.8 1.0 O A:HOH821 4.8 34.1 1.0

S.Nawarathnage, R.D.Bunn, C.Stewart, T.Doukov, J.D.Moody. The Ubiquitin-Associated Domain of Human Thirty-Eight Negative Kinase-1 To Be Published.