Chlorine in PDB 7tfg: Structure of Mouse Double Minute 2 Homolog (MDM2) Ring Domain in Complex with MA242
Enzymatic activity of Structure of Mouse Double Minute 2 Homolog (MDM2) Ring Domain in Complex with MA242
All present enzymatic activity of Structure of Mouse Double Minute 2 Homolog (MDM2) Ring Domain in Complex with MA242:
2.3.2.27;
2.3.2.27;
Protein crystallography data
The structure of Structure of Mouse Double Minute 2 Homolog (MDM2) Ring Domain in Complex with MA242, PDB code: 7tfg
was solved by
M.Luo,
J.R.Terrell,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 33.03 / 1.68 |
| Space group | P 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 29.351, 39.794, 52.095, 84.44, 85.88, 89.98 |
| R / Rfree (%) | 16.8 / 20.1 |
Other elements in 7tfg:
The structure of Structure of Mouse Double Minute 2 Homolog (MDM2) Ring Domain in Complex with MA242 also contains other interesting chemical elements:
| Zinc | (Zn) | 8 atoms |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of Mouse Double Minute 2 Homolog (MDM2) Ring Domain in Complex with MA242
(pdb code 7tfg). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of Mouse Double Minute 2 Homolog (MDM2) Ring Domain in Complex with MA242, PDB code: 7tfg:
In total only one binding site of Chlorine was determined in the Structure of Mouse Double Minute 2 Homolog (MDM2) Ring Domain in Complex with MA242, PDB code: 7tfg:
Chlorine binding site 1 out of 1 in 7tfg
Go back to
Chlorine Binding Sites List in 7tfg
Chlorine binding site 1 out
of 1 in the Structure of Mouse Double Minute 2 Homolog (MDM2) Ring Domain in Complex with MA242
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Structure of Mouse Double Minute 2 Homolog (MDM2) Ring Domain in Complex with MA242 within 5.0Å range:
|
Reference:
J.R.Terrell,
S.Tang,
O.O.Faniyi,
I.H.Jeong,
J.Yin,
B.Nijampatnam,
S.E.Velu,
W.Wang,
R.Zhang,
M.Luo.
Structural Studies of Antitumor Compounds That Target the Ring Domain of MDM2. Protein Sci. V. 31 E4367 2022.
ISSN: ESSN 1469-896X
PubMed: 35900024
DOI: 10.1002/PRO.4367
Page generated: Tue Apr 4 21:49:08 2023
ISSN: ESSN 1469-896X
PubMed: 35900024
DOI: 10.1002/PRO.4367
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