Chlorine in PDB 7ti1: Structure of Ampc Bound to Rpx-7063 at 2.0A

All present enzymatic activity of Structure of Ampc Bound to Rpx-7063 at 2.0A:
3.5.2.6;

The structure of Structure of Ampc Bound to Rpx-7063 at 2.0A, PDB code: 7ti1 was solved by M.C.Clifton, J.Abendroth, T.E.Edwards, S.J.Hecker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.00
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	68.96, 77.98, 62.26, 90, 90, 90
R / Rfree (%)	16 / 21.4

The binding sites of Chlorine atom in the Structure of Ampc Bound to Rpx-7063 at 2.0A (pdb code 7ti1). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of Ampc Bound to Rpx-7063 at 2.0A, PDB code: 7ti1:

Chlorine binding site 1 out of 1 in the Structure of Ampc Bound to Rpx-7063 at 2.0A


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Ampc Bound to Rpx-7063 at 2.0A within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl404 b:43.9 occ:1.00 CG A:PRO185 3.7 16.3 1.0 N A:PRO185 3.8 16.1 1.0 CB A:LYS184 3.8 15.9 1.0 CD A:PRO185 3.9 15.8 1.0 CA A:PRO185 3.9 17.1 1.0 CD1 A:TYR112 4.0 16.6 1.0 C A:LYS184 4.0 15.8 1.0 CB A:PRO185 4.3 16.5 1.0 O A:LYS184 4.4 16.1 1.0 CA A:TYR112 4.4 16.3 1.0 O A:TYR112 4.6 16.9 1.0 CA A:LYS184 4.6 15.5 1.0 CB A:TYR112 4.7 15.9 1.0 O A:ARG111 4.8 17.1 1.0 CG A:TYR112 4.9 16.1 1.0 CE A:LYS184 4.9 17.1 1.0 CE1 A:TYR112 4.9 17.2 1.0 CG A:LYS184 4.9 16.5 1.0 C A:TYR112 4.9 16.4 1.0 O A:HOH545 5.0 32.0 1.0

K.R.Reddy, M.Totrov, O.Lomovskaya, D.C.Griffith, Z.Tarazi, M.C.Clifton, S.J.Hecker. Broad-Spectrum Cyclic Boronate Beta-Lactamase Inhibitors Featuring An Intramolecular Prodrug For Oral Bioavailability To Be Published.