Chlorine in PDB 7u0a: Crystal Structure of C77G12 Fab in Complex with Sars-Cov-2 S Fusion Peptide

The structure of Crystal Structure of C77G12 Fab in Complex with Sars-Cov-2 S Fusion Peptide, PDB code: 7u0a was solved by M.A.Tortorici, D.Veesler, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.15 / 1.70
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	45.227, 64.056, 78.813, 90, 93.33, 90
R / Rfree (%)	15.4 / 18.7

The binding sites of Chlorine atom in the Crystal Structure of C77G12 Fab in Complex with Sars-Cov-2 S Fusion Peptide (pdb code 7u0a). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of C77G12 Fab in Complex with Sars-Cov-2 S Fusion Peptide, PDB code: 7u0a:

Chlorine binding site 1 out of 1 in the Crystal Structure of C77G12 Fab in Complex with Sars-Cov-2 S Fusion Peptide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of C77G12 Fab in Complex with Sars-Cov-2 S Fusion Peptide within 5.0Å range: probe atom residue distance (Å) B Occ H:Cl301 b:21.0 occ:1.00 O H:HOH484 2.8 21.3 1.0 O H:HOH607 3.1 43.1 1.0 N L:PHE98 3.3 20.3 1.0 N H:TRP47 3.3 16.3 1.0 CA L:THR97 3.6 17.0 1.0 CA H:GLU46 3.8 14.9 1.0 CD1 L:PHE98 3.9 20.6 1.0 C L:THR97 4.0 16.9 1.0 C H:GLU46 4.0 17.2 1.0 CB L:PHE98 4.1 15.6 1.0 O L:HOH382 4.1 18.8 1.0 CB L:THR97 4.2 18.8 1.0 O H:LEU45 4.2 18.5 1.0 CB H:TRP47 4.2 16.1 1.0 CA L:PHE98 4.2 16.5 1.0 O L:PHE96 4.3 18.6 1.0 CA H:TRP47 4.3 14.4 1.0 O L:PHE98 4.4 19.3 1.0 CG2 L:THR97 4.4 20.6 1.0 CG L:PHE98 4.5 18.6 1.0 CB H:GLU46 4.5 19.0 1.0 N L:THR97 4.7 17.2 1.0 O H:TRP47 4.7 19.0 1.0 CG H:GLU46 4.8 24.2 1.0 N H:GLU46 4.8 16.4 1.0 C L:PHE98 4.8 20.9 1.0 C H:LEU45 4.9 19.4 1.0 CE1 L:PHE98 4.9 17.1 1.0 C L:PHE96 4.9 20.3 1.0 O L:HOH499 5.0 54.8 1.0

J.S.Low, J.Jerak, M.A.Tortorici, M.Mccallum, D.Pinto, A.Cassotta, M.Foglierini, F.Mele, R.Abdelnabi, B.Weynand, J.Noack, M.Montiel-Ruiz, S.Bianchi, F.Benigni, N.Sprugasci, A.Joshi, J.E.Bowen, C.Stewart, M.Rexhepaj, A.C.Walls, D.Jarrossay, D.Morone, P.Paparoditis, C.Garzoni, P.Ferrari, A.Ceschi, J.Neyts, L.A.Purcell, G.Snell, D.Corti, A.Lanzavecchia, D.Veesler, F.Sallusto. ACE2-Binding Exposes the Sars-Cov-2 Fusion Peptide to Broadly Neutralizing Coronavirus Antibodies. Science V. 377 735 2022.
ISSN: ESSN 1095-9203
PubMed: 35857703
DOI: 10.1126/SCIENCE.ABQ2679