Chlorine in PDB 7u24: Cryo-Em Structure of the Pancreatic Atp-Sensitive Potassium Channel Bound to Atp and Glibenclamide with KIR6.2-Ctd in the Up Conformation

The binding sites of Chlorine atom in the Cryo-Em Structure of the Pancreatic Atp-Sensitive Potassium Channel Bound to Atp and Glibenclamide with KIR6.2-Ctd in the Up Conformation (pdb code 7u24). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryo-Em Structure of the Pancreatic Atp-Sensitive Potassium Channel Bound to Atp and Glibenclamide with KIR6.2-Ctd in the Up Conformation, PDB code: 7u24:

Chlorine binding site 1 out of 1 in the Cryo-Em Structure of the Pancreatic Atp-Sensitive Potassium Channel Bound to Atp and Glibenclamide with KIR6.2-Ctd in the Up Conformation


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of the Pancreatic Atp-Sensitive Potassium Channel Bound to Atp and Glibenclamide with KIR6.2-Ctd in the Up Conformation within 5.0Å range: probe atom residue distance (Å) B Occ E:Cl2001 b:33.8 occ:1.00 CL1 E:GBM2001 0.0 33.8 1.0 C31 E:GBM2001 1.8 33.8 1.0 NH2 E:ARG306 2.7 30.9 1.0 C32 E:GBM2001 2.8 33.8 1.0 C29 E:GBM2001 2.8 33.8 1.0 CB E:PRO589 3.7 40.5 1.0 CA E:PRO589 3.9 40.5 1.0 CG E:PRO589 3.9 40.5 1.0 CZ E:ARG306 4.0 30.9 1.0 C30 E:GBM2001 4.0 33.8 1.0 C27 E:GBM2001 4.0 33.8 1.0 OD1 E:ASN437 4.4 35.4 1.0 N E:PRO589 4.4 40.5 1.0 NH1 E:ARG306 4.5 30.9 1.0 C28 E:GBM2001 4.6 33.8 1.0 O E:THR588 4.8 40.0 1.0 CG2 E:THR588 4.8 40.0 1.0 CD E:PRO589 4.8 40.5 1.0 C E:THR588 4.8 40.0 1.0 NE E:ARG306 4.9 30.9 1.0 CD2 E:LEU592 4.9 42.6 1.0

M.W.Sung, C.M.Driggers, B.Mostofian, J.D.Russo, B.L.Patton, D.M.Zuckerman, S.L.Shyng. Ligand-Mediated Structural Dynamics of A Mammalian Pancreatic K Atp Channel. J.Mol.Biol. V. 434 67789 2022.
ISSN: ESSN 1089-8638
PubMed: 35964676
DOI: 10.1016/J.JMB.2022.167789