Chlorine in PDB 7uid: Thyclotides Peptide Nucleic Acid in Complex with Dna

Protein crystallography data

The structure of Thyclotides Peptide Nucleic Acid in Complex with Dna, PDB code: 7uid was solved by I.Botos, D.H.Appella, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 35.62 / 2.00
Space group I 2 2 2
Cell size a, b, c (Å), α, β, γ (°) 54.286, 64.098, 71.244, 90, 90, 90
R / Rfree (%) 23.2 / 26.5

Other elements in 7uid:

The structure of Thyclotides Peptide Nucleic Acid in Complex with Dna also contains other interesting chemical elements:

Iodine (I) 2 atoms
Zinc (Zn) 6 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Thyclotides Peptide Nucleic Acid in Complex with Dna (pdb code 7uid). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Thyclotides Peptide Nucleic Acid in Complex with Dna, PDB code: 7uid:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 7uid

Go back to Chlorine Binding Sites List in 7uid
Chlorine binding site 1 out of 2 in the Thyclotides Peptide Nucleic Acid in Complex with Dna


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Thyclotides Peptide Nucleic Acid in Complex with Dna within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl101

b:46.3
occ:1.00
I1 B:NSF1 2.3 26.0 0.2
C17 B:NSF1 4.2 26.2 1.0
C18 B:NSF1 5.0 26.2 1.0
O20 B:NSF1 5.0 26.2 1.0

Chlorine binding site 2 out of 2 in 7uid

Go back to Chlorine Binding Sites List in 7uid
Chlorine binding site 2 out of 2 in the Thyclotides Peptide Nucleic Acid in Complex with Dna


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Thyclotides Peptide Nucleic Acid in Complex with Dna within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl101

b:37.1
occ:1.00
I1 D:NSF1 2.3 14.3 0.3
O D:HOH207 4.0 22.7 1.0
O D:HOH215 4.1 32.2 1.0
C17 D:NSF1 4.3 15.2 1.0
O20 D:NSF1 4.9 14.9 1.0

Reference:

H.Zheng, V.Clausse, I.Botos, H.Amarasekara, S.J.Mazur, D.H.Appella. Thyclotides, (R,R)-Trans-Tetrahydrofuran-Constrained Peptide Nucleic Acids Enhance Oligonucleotide Binding and Cellular Uptake to Target Microrna-21 To Be Published.
Page generated: Tue Apr 11 13:09:15 2023

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy