Chlorine in PDB 7upi: Cryo-Em Structure of SHOC2-PP1C-Mras Holophosphatase Complex

All present enzymatic activity of Cryo-Em Structure of SHOC2-PP1C-Mras Holophosphatase Complex:
3.1.3.16; 3.6.5.2;

The structure of Cryo-Em Structure of SHOC2-PP1C-Mras Holophosphatase Complex also contains other interesting chemical elements:

Manganese	(Mn)	2 atoms
Magnesium	(Mg)	1 atom

The binding sites of Chlorine atom in the Cryo-Em Structure of SHOC2-PP1C-Mras Holophosphatase Complex (pdb code 7upi). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryo-Em Structure of SHOC2-PP1C-Mras Holophosphatase Complex, PDB code: 7upi:

Chlorine binding site 1 out of 1 in the Cryo-Em Structure of SHOC2-PP1C-Mras Holophosphatase Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of SHOC2-PP1C-Mras Holophosphatase Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl403 b:53.1 occ:1.00 NH1 B:ARG96 3.0 73.5 1.0 NE2 B:HIS125 3.1 52.5 1.0 CD2 B:HIS125 3.6 50.2 1.0 MN B:MN402 3.7 82.0 1.0 NH1 B:ARG221 3.7 54.7 1.0 ND2 B:ASN124 3.8 42.1 1.0 CZ B:ARG96 3.8 72.0 1.0 NH2 B:ARG96 3.9 66.9 1.0 MN B:MN401 3.9 67.1 1.0 OD1 B:ASN124 4.2 53.9 1.0 CE1 B:HIS125 4.3 55.2 1.0 CE1 B:HIS248 4.4 42.6 1.0 CG B:ASN124 4.4 39.8 1.0 OD2 B:ASP92 4.5 46.1 1.0 ND1 B:HIS248 4.7 39.2 1.0 CZ B:ARG221 4.8 52.4 1.0 O B:HIS248 4.8 50.1 1.0 CE1 B:HIS66 4.8 45.6 1.0 CG B:HIS125 4.9 47.8 1.0 NE2 B:HIS66 5.0 52.9 1.0 NE B:ARG96 5.0 68.7 1.0 OH B:TYR272 5.0 69.9 1.0

J.J.Kwon, B.Hajian, Y.Bian, L.C.Young, A.J.Amor, J.R.Fuller, C.V.Fraley, A.M.Sykes, J.So, J.Pan, L.Baker, S.J.Lee, D.B.Wheeler, D.L.Mayhew, N.S.Persky, X.Yang, D.E.Root, A.M.Barsotti, A.W.Stamford, C.K.Perry, A.Burgin, F.Mccormick, C.T.Lemke, W.C.Hahn, A.J.Aguirre. Structure-Function Analysis of the SHOC2-Mras-PP1C Holophosphatase Complex. Nature V. 609 408 2022.
ISSN: ESSN 1476-4687
PubMed: 35831509
DOI: 10.1038/S41586-022-04928-2