Chlorine in PDB 7v8k: Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with L- Proline

All present enzymatic activity of Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with L- Proline:
6.1.1.15;

The structure of Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with L- Proline, PDB code: 7v8k was solved by Y.Manickam, N.Malhotra, A.Sharma, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	68.29 / 2.47
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	77.196, 81.673, 104.66, 90, 102.94, 90
R / Rfree (%)	16.7 / 21.9

The binding sites of Chlorine atom in the Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with L- Proline (pdb code 7v8k). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with L- Proline, PDB code: 7v8k:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with L- Proline


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with L- Proline within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl910 b:54.6 occ:1.00 N A:ILE655 3.2 29.2 1.0 CE A:LYS643 3.5 42.9 1.0 CG A:ARG654 3.8 49.5 1.0 O A:ILE655 3.8 40.6 1.0 CA A:ARG654 4.0 33.7 1.0 CB A:ILE655 4.0 30.9 1.0 CA A:ILE655 4.1 27.6 1.0 C A:ARG654 4.1 35.9 1.0 CG1 A:ILE655 4.3 29.9 1.0 CD A:LYS643 4.4 39.3 1.0 C A:ILE655 4.4 36.0 1.0 NZ A:LYS643 4.4 53.6 1.0 CB A:ARG654 4.5 35.5 1.0 O A:VAL653 4.6 31.4 1.0 CD1 A:ILE655 4.6 38.2 1.0 CD A:ARG654 5.0 60.6 1.0

Chlorine binding site 2 out of 3 in the Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with L- Proline


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with L- Proline within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl911 b:74.2 occ:1.00 OE2 A:GLU497 4.1 68.8 1.0 CD2 A:LEU561 4.1 25.9 1.0 CD2 A:TRP501 4.2 25.3 1.0 CG A:TRP501 4.3 26.7 1.0 CE2 A:TRP501 4.4 24.3 1.0 CD1 A:TRP501 4.5 23.5 1.0 NE1 A:TRP501 4.6 26.1 1.0 CE3 A:TRP501 4.6 20.9 1.0 CB A:TRP501 4.7 25.9 1.0 CD A:GLU497 4.9 64.8 1.0 CZ2 A:TRP501 4.9 20.7 1.0 CE A:LYS538 5.0 59.3 1.0

Chlorine binding site 3 out of 3 in the Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with L- Proline


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with L- Proline within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl911 b:88.2 occ:1.00 CA B:GLY793 4.2 67.1 1.0 CZ B:ARG828 4.4 49.2 1.0 NE B:ARG828 4.4 47.4 1.0 NH2 B:ARG828 4.5 46.3 1.0 CB B:SER777 4.8 75.3 1.0 NH1 B:ARG828 4.8 52.3 1.0 CD B:ARG828 4.9 41.9 1.0 N B:GLY793 4.9 70.2 1.0

Y.Manickam, N.Malhotra, A.Sharma. Toxoplasma Gondii Prolyl-Trna Synthetase (Tgprs) in Complex with L-Proline To Be Published.