Chlorine in PDB 7vob: The Crystal Structure of A Radical Sam Enzyme Blse Involved in the Biosynthesis of Blasticidin S

The structure of The Crystal Structure of A Radical Sam Enzyme Blse Involved in the Biosynthesis of Blasticidin S, PDB code: 7vob was solved by X.L.Hou, J.H.Zhou, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.18 / 2.09
Space group	I 41 2 2
Cell size a, b, c (Å), α, β, γ (°)	164.293, 164.293, 157.324, 90, 90, 90
R / Rfree (%)	22.3 / 23.7

The structure of The Crystal Structure of A Radical Sam Enzyme Blse Involved in the Biosynthesis of Blasticidin S also contains other interesting chemical elements:

Iron

(Fe)

8 atoms

The binding sites of Chlorine atom in the The Crystal Structure of A Radical Sam Enzyme Blse Involved in the Biosynthesis of Blasticidin S (pdb code 7vob). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the The Crystal Structure of A Radical Sam Enzyme Blse Involved in the Biosynthesis of Blasticidin S, PDB code: 7vob:

Chlorine binding site 1 out of 1 in the The Crystal Structure of A Radical Sam Enzyme Blse Involved in the Biosynthesis of Blasticidin S


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Crystal Structure of A Radical Sam Enzyme Blse Involved in the Biosynthesis of Blasticidin S within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl410 b:53.4 occ:1.00 O C:HOH631 3.0 57.0 1.0 O C:HOH607 3.1 49.7 1.0 O C:HOH583 3.1 55.6 1.0 NH1 C:ARG340 3.3 50.8 1.0 NH2 C:ARG340 3.3 49.2 1.0 N C:GLY227 3.4 47.0 1.0 CZ C:ARG340 3.7 51.2 1.0 CA C:LEU226 3.9 48.1 1.0 C C:LEU226 4.1 53.0 1.0 CB C:LEU226 4.3 46.6 1.0 CD2 C:LEU226 4.3 47.0 1.0 CA C:GLY227 4.3 47.5 1.0 NE2 C:GLN343 4.4 46.5 1.0 O C:HOH529 4.5 54.5 1.0 O C:HOH601 4.5 51.9 1.0 O C:HOH552 4.6 45.2 1.0 CG C:GLN343 4.7 42.7 1.0 CD C:GLN343 4.8 51.3 1.0 O C:HOH561 4.9 55.9 1.0 CG C:LEU226 5.0 49.5 1.0

Y.H.Lee, X.Hou, R.Chen, J.Feng, X.Liu, M.W.Ruszczycky, J.M.Gao, B.Wang, J.Zhou, H.W.Liu. Radical S -Adenosyl Methionine Enzyme Blse Catalyzes A Radical-Mediated 1,2-Diol Dehydration During the Biosynthesis of Blasticidin S. J.Am.Chem.Soc. V. 144 4478 2022.
ISSN: ESSN 1520-5126
PubMed: 35238201
DOI: 10.1021/JACS.1C12010