Chlorine in PDB 7vui: Cryo-Em Structure of A Class A Orphan Gpcr

All present enzymatic activity of Cryo-Em Structure of A Class A Orphan Gpcr:
3.2.1.8;

The structure of Cryo-Em Structure of A Class A Orphan Gpcr also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Chlorine atom in the Cryo-Em Structure of A Class A Orphan Gpcr (pdb code 7vui). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Cryo-Em Structure of A Class A Orphan Gpcr, PDB code: 7vui:

Chlorine binding site 1 out of 1 in the Cryo-Em Structure of A Class A Orphan Gpcr


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Cryo-Em Structure of A Class A Orphan Gpcr within 5.0Å range: probe atom residue distance (Å) B Occ R:Cl401 b:75.8 occ:1.00 CL1 R:7ZQ401 0.0 75.8 1.0 C3 R:7ZQ401 1.8 75.8 1.0 C2 R:7ZQ401 2.8 75.8 1.0 C4 R:7ZQ401 2.8 75.8 1.0 OH R:TYR174 3.0 77.6 1.0 CD1 R:ILE184 3.5 64.9 1.0 CG1 R:ILE184 4.0 64.9 1.0 C1 R:7ZQ401 4.0 75.8 1.0 C5 R:7ZQ401 4.0 75.8 1.0 CD1 R:ILE169 4.2 78.7 1.0 CD2 R:HIS251 4.3 73.1 1.0 CZ R:TYR174 4.3 77.6 1.0 C6 R:7ZQ401 4.6 75.8 1.0 CB R:PRO167 4.7 69.8 1.0 CZ2 R:TRP166 4.8 69.6 1.0 CG R:PRO167 4.8 69.8 1.0 CG2 R:ILE248 4.8 66.9 1.0 O R:PRO167 4.9 69.8 1.0 CB R:ILE248 5.0 66.9 1.0 NE1 R:TRP166 5.0 69.6 1.0

Y.Zhou, H.Daver, B.Trapkov, L.Wu, M.Wu, K.Harpsoe, P.R.Gentry, K.Liu, M.Larionova, J.Liu, N.Chen, H.Brauner-Osborne, D.E.Gloriam, T.Hua, Z.J.Liu. Molecular Insights Into Ligand Recognition and G Protein Coupling of the Neuromodulatory Orphan Receptor GPR139. Cell Res. 2021.
ISSN: ISSN 1001-0602
PubMed: 34916631
DOI: 10.1038/S41422-021-00591-W